HitPredict

Interactor 1: AATC (P17174)
Aspartate aminotransferase, cytoplasmic (cAspAT) (EC 2.6.1.1) (EC 2.6.1.3) (Cysteine aminotransferase, cytoplasmic) (Cysteine transaminase, cytoplasmic) (cCAT) (Glutamate oxaloacetate transaminase 1) (Transaminase A)
Gene: GOT1

Interactor 2: SPB8 (P50452)
Serpin B8 (Cytoplasmic antiproteinase 2) (CAP-2) (CAP2) (Peptidase inhibitor 8) (PI-8)
Gene: SERPINB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 413 Hs			1 374
+	Hs
		397007 AATC_HUMAN (1-413): 0: 711: 100.00		PAI2_HUMAN (1-374): 4.69e-159: 454: 42.79
+	Hs
		565881 AATC_HUMAN (1-413): 0: 711: 100.00		ILEU_HUMAN (1-374): 1.27e-159: 454: 51.72
+	Hs
		565898 AATC_HUMAN (1-413): 0: 711: 100.00		SPB4_HUMAN (1-374): 3.16e-153: 438: 44.64
+	Hs
		565876 AATC_HUMAN (1-413): 0: 711: 100.00		SPB3_HUMAN (1-374): 7.84e-152: 435: 43.62
+	Hs
		271850 AATC_HUMAN (1-413): 0: 711: 100.00		SPB7_HUMAN (1-374): 1.65e-144: 416: 36.36
+	Hs
		344272 AATC_HUMAN (1-413): 0: 711: 100.00		AACT_HUMAN (4-374): 7.5e-141: 408: 33.25
+	Hs
		565888 AATC_HUMAN (1-413): 0: 711: 100.00		SPB5_HUMAN (1-374): 8.53e-141: 406: 37.73
+	Hs
		344214 AATC2_HUMAN (1-409): 0: 528: 40.34		A1AT_HUMAN (2-374): 1.43e-139: 404: 31.75