HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: CDK16 (Q00536)
Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)
Gene: CDK16

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 496
+	Hs
		625131 RFA1_HUMAN (1-616): 0: 781: 100.00		CDK2_HUMAN (162-456): 6.05e-145: 418: 53.54
+	Hs
		414753 RFA1_HUMAN (1-616): 0: 781: 100.00		CDK1_HUMAN (162-451): 2.98e-136: 397: 51.88
+	Hs
		650694 RFA1_HUMAN (1-616): 0: 781: 100.00		CDK7_HUMAN (160-481): 5.55e-132: 387: 37.69
+	Hs
		650972 RFA1_HUMAN (1-616): 0: 781: 100.00		CDK5_HUMAN (162-452): 9.2e-133: 387: 55.97