HitPredict

Interactor 1: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Interactor 2: LCP2 (Q13094)
Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76)
Gene: LCP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	10204582, 9716598, 10477741, 19635790
Identification Methods	affinity chromatography technology, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 906 Hs			1 533
+	Hs
		651389 CBL_HUMAN (1-906): 0: 882: 100.00		BLNK_HUMAN (75-520): 1.01e-33: 135: 24.28
+	Mm
		1189574 CBLB_MOUSE (23-901): 0: 764: 46.56		LCP2_MOUSE (1-531): 1.4e-72: 242: 80.98
+	Hs
		651379 CBL_HUMAN (1-906): 0: 882: 100.00		TENS4_HUMAN (189-512): 1.18e-26: 116: 16.52
+	Dm
		119660 M9PB30_DROME (512-898): 3.9e-13: 76.2: 9.32		M9PB30_DROME (72-360): 6.2e-09: 61.2: 10.73
+	Hs
		590235 MUC1_HUMAN (466-906): 1.31e-12: 74.2: 13.54		MUC1_HUMAN (191-473): 9.08e-09: 60.4: 10.88
+	Mm
		1455913 PCLO_MOUSE (448-855): 2.58e-10: 66.9: 12.23		PCLO_MOUSE (43-460): 5.13e-09: 61.5: 12.27