Protein: TENS4
Tensin-4 (C-terminal tensin-like protein)

Gene: TENS4, TNS4
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q8IZW8

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005925 - focal adhesion
GO:0008104 - intracellular protein localization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

363552

EGFR
Epidermal growth factor receptor

3

20

High-throughput

0.834

High

840919

TXK
Tyrosine-protein kinase TXK

2

20

High-throughput

0.783

High

699803

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

7

High-throughput

0.767

High

1062384

PP2BA
Protein phosphatase 3 catalytic subunit alpha

3

8

High-throughput

0.665

High

1145748

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

651379

CBL
E3 ubiquitin-protein ligase CBL

2

17

Small-scale

0.624

High

472094

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.619

High

572065

TRI27
Zinc finger protein RFP

2

7

High-throughput

0.606

High

623438

RO52
E3 ubiquitin-protein ligase TRIM21

2

6

High-throughput

0.606

High

1144849

RABE1
Rab GTPase-binding effector protein 1

2

3

High-throughput

0.606

High

1226844

KAZRN
Kazrin

2

1

High-throughput

0.606

High

1317110

CARD9
Caspase recruitment domain-containing protein 9

2

2

High-throughput

0.606

High

1317113

ZRAN1
Ubiquitin thioesterase ZRANB1

2

7

High-throughput

0.606

High

191364

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

2

1

High-throughput

0.594

High

269282

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

641622

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.579

High

1317112

PIHD1
PIH1 domain-containing protein 1

2

1

High-throughput

0.553

High

143872

NDKM
Nucleoside diphosphate kinase, mitochondrial

2

1

High-throughput

0.542

High

520198

ANDR
Androgen receptor

1

20

High-throughput

0.536

High

1106490

GAB1
GRB2-associated-binding protein 1

1

11

High-throughput

0.536

High

593856

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

7

High-throughput

0.536

High

873477

PP2BC
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

1

7

High-throughput

0.536

High

1136915

ABRX2
BRISC complex subunit Abraxas 2

1

2

High-throughput

0.536

High

1144778

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

1

1

High-throughput

0.536

High

1317106

KCTD4
BTB/POZ domain-containing protein KCTD4

2

10

High-throughput

0.526

High

730756

1433S
14-3-3 protein sigma

1

20

High-throughput

0.515

High

359840

DYR
Dihydrofolate reductase

1

0

High-throughput

0.513

High

451625

GPX1
Glutathione peroxidase 1

1

0

High-throughput

0.513

High

989913

CANB1
Calcineurin subunit B type 1

1

0

High-throughput

0.513

High

1317108

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1317111

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.513

High

1281654

ZER1
Protein zer-1 homolog

1

1

High-throughput

0.489

High

1317107

NPAS1
Neuronal PAS domain-containing protein 1

1

5

High-throughput

0.489

High

1317109

ZY11B
Protein zyg-11 homolog B

1

1

High-throughput

0.489

High

404215

GCR
Glucocorticoid receptor

1

20

Small-scale

0.481

High

872519

SOX2
Transcription factor SOX-2

1

18

High-throughput

0.479

High

888183

MCM2
DNA replication licensing factor MCM2

1

3

High-throughput

0.479

High

70347

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

1288057

RIP
RPA-interacting protein

2

0

High-throughput

0.310

High

1317105

GSTCD
Glutathione S-transferase C-terminal domain-containing protein

2

0

High-throughput

0.310

High

690043

CRBB3
Beta-crystallin B3

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025