HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: TYRO3 (Q06418)
Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)
Gene: TYRO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 592 Hs			1 890
+	Hs
		161056 CLGN_HUMAN (11-546): 0: 652: 59.85		TYRO3_HUMAN (1-890): 0: 746: 100.00
+	Hs
		654090 CALX_HUMAN (1-592): 0: 786: 100.00		EPHA3_HUMAN (125-821): 0: 552: 19.39
+	Hs
		654091 CALX_HUMAN (1-592): 0: 786: 100.00		EPHA8_HUMAN (116-808): 3.82e-166: 511: 20.03
+	Hs
		654413 CALX_HUMAN (1-592): 0: 786: 100.00		EPHAA_HUMAN (203-842): 1.14e-129: 416: 23.35
+	Hs
		441438 CALX_HUMAN (1-592): 0: 786: 100.00		MET_HUMAN (495-790): 3.89e-65: 240: 41.67
+	Hs
		435545 CALX_HUMAN (1-592): 0: 786: 100.00		IGF1R_HUMAN (333-779): 3.39e-61: 228: 32.53
+	Hs
		411305 CALX_HUMAN (1-592): 0: 786: 100.00		INSR_HUMAN (292-790): 2.17e-60: 226: 31.15
+	Hs
		445825 CALX_HUMAN (1-592): 0: 786: 100.00		ROS1_HUMAN (279-787): 2.73e-55: 211: 30.76
+	Hs
		434139 CALX_HUMAN (1-592): 0: 786: 100.00		RET_HUMAN (514-790): 1.89e-55: 210: 39.93
+	Hs
		601462 CALX_HUMAN (1-592): 0: 786: 100.00		FGFR2_HUMAN (2-234): 1.07e-43: 172: 13.68
+	Hs
		161004 CLGN_HUMAN (11-546): 0: 652: 59.85		MET_HUMAN (495-790): 3.89e-65: 240: 41.67
+	Hs
		507869 CALX_HUMAN (1-592): 0: 786: 100.00		FGFR1_HUMAN (6-230): 2.63e-19: 95.6: 18.22
+	Hs
		161003 CLGN_HUMAN (11-546): 0: 652: 59.85		IGF1R_HUMAN (333-779): 3.39e-61: 228: 32.53
+	Hs
		160999 CLGN_HUMAN (11-546): 0: 652: 59.85		INSR_HUMAN (292-790): 2.17e-60: 226: 31.15
+	Hs
		654101 CALX_HUMAN (1-592): 0: 786: 100.00		UFO_HUMAN (6-344): 1.91e-14: 79.8: 14.56
+	Hs
		161002 CLGN_HUMAN (11-546): 0: 652: 59.85		RET_HUMAN (514-790): 1.89e-55: 210: 39.93
+	Rn
		544766 CALR_RAT (67-470): 7.8e-147: 431: 37.35		INSR_RAT (232-788): 7.04e-127: 416: 27.65
+	Hs
		161008 CLGN_HUMAN (11-546): 0: 652: 59.85		FGFR1_HUMAN (6-230): 2.63e-19: 95.6: 18.22
+	Hs
		441437 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		MET_HUMAN (495-790): 3.89e-65: 240: 41.67
+	Hs
		653493 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		UFO_HUMAN (6-344): 1.91e-14: 79.8: 14.56