HitPredict

Interactor 1: EPOP (A6NHQ4)
Elongin BC and Polycomb repressive complex 2-associated protein (Proline-rich protein 28)
Gene: EPOP

Interactor 2: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26496610, 27705803, 24981860
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0035098 - ESC/E(Z) complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 379 Hs			1 441
+	Mm
		92778 D3Z656_MOUSE (7-378): 4.12e-42: 159: 14.65		EED_MOUSE (1-441): 1.63e-90: 283: 100.00
+	Mm
		1274393 EPOP_MOUSE (1-378): 1.88e-35: 135: 69.31		EED_MOUSE (1-441): 1.63e-90: 283: 100.00
+	Hs
		285316 SKDA1_HUMAN (218-375): 1.36e-15: 80.6: 30.77		EED_HUMAN (1-441): 1.63e-90: 283: 100.00
+	Hs
		1217419 OBSCN_HUMAN (2-334): 1e-26: 114: 14.44		POC1B_HUMAN (186-440): 3.47e-46: 167: 15.56
+	Mm
		965395 KMT2C_MOUSE (3-365): 5.63e-21: 97.1: 15.27		WDR5_MOUSE (335-440): 3.34e-14: 75.4: 15.09
+	Hs
		1380165 PRR36_HUMAN (2-364): 8.42e-09: 59.4: 12.77		FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32
+	Hs
		965097 KMT2C_HUMAN (3-365): 1.17e-18: 90.2: 14.43		WDR5_HUMAN (335-440): 3.34e-14: 75.4: 15.09
+	Hs
		1361892 TITIN_HUMAN (2-350): 9.87e-09: 59.5: 12.22		SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29