Interactor 1: SUH (P28159)
Suppressor of hairless protein (J kappa-recombination signal-binding protein) (RBP-J kappa)
Gene: Su(H)

Interactor 2: HLES (Q02308)
Protein hairless
Gene: H

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.766

The method score is based on:

Property Details
Experiments 7958912, 21737682, 11378391, 22125648, 27404588, 9347918, 26448463, 28861687, 25452105, 28928428, 25363277, 25242320, 30694174, 30612166, 31615108, 24282610, 25650119, 25588307, 20231316, 15710747 and 3 others

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Identification Methods affinity chromatography technology, pull down, two hybrid, x-ray crystallography, isothermal titration calorimetry, two hybrid fragment pooling approach, experimental interaction detection
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0008586 - imaginal disc-derived wing vein morphogenesis
GO:0016360 - sensory organ precursor cell fate determination
GO:0045746 - negative regulation of Notch signaling pathway
and 2 others

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Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 594
Dm

1 1077
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024