Protein: UBP10
Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Disrupter of telomere silencing protein 4) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10)

Gene: UBP10
Organism: Saccharomyces cerevisiae S288C
Interactions: 215
UniProt ID: P53874

Gene Ontology (top 5):
GO:0000781 - chromosome, telomeric region
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

924167

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

3

16

Small-scale

0.850

High

509670

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

2

20

Small-scale

0.778

High

924207

NOP56
Nucleolar protein 56

2

8

High-throughput

0.754

High

779147

DHR2
Probable ATP-dependent RNA helicase DHR2

6

12

Small-scale

0.735

High

550679

SIR4
Regulatory protein SIR4

5

1

Small-scale

0.717

High

754315

DCA13
Protein SOF1

1

17

High-throughput

0.698

High

924193

RRP9
Ribosomal RNA-processing protein 9

1

20

High-throughput

0.698

High

918796

UTP22
U3 small nucleolar RNA-associated protein 22

4

2

Small-scale

0.696

High

381197

H2B1
Histone H2B.1

4

20

Small-scale

0.686

High

673582

NLE1
Ribosome assembly protein 4

1

19

High-throughput

0.665

High

381583

H2B2
Histone H2B.2

3

20

Small-scale

0.646

High

579844

HSC82
ATP-dependent molecular chaperone HSC82

3

7

High-throughput

0.643

High

534292

RPA1
DNA-directed RNA polymerase I subunit RPA190

2

5

Small-scale

0.624

High

633180

MAK11
Protein MAK11

1

20

High-throughput

0.618

High

637256

PWP1
Periodic tryptophan protein 1

1

20

High-throughput

0.618

High

678436

PWP2
Periodic tryptophan protein 2

1

15

High-throughput

0.618

High

737757

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

9

High-throughput

0.618

High

796403

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

19

Small-scale

0.618

High

817607

UTP7
U3 small nucleolar RNA-associated protein 7

1

15

High-throughput

0.618

High

850331

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

17

Small-scale

0.618

High

924181

UTP17
NET1-associated nuclear protein 1

1

13

High-throughput

0.618

High

924189

UTP13
U3 small nucleolar RNA-associated protein 13

1

20

High-throughput

0.618

High

924195

UTP4
U3 small nucleolar RNA-associated protein 4

1

15

High-throughput

0.618

High

924209

NOP58
Nucleolar protein 58

1

8

High-throughput

0.618

High

666514

DBP2
ATP-dependent RNA helicase DBP2

2

11

High-throughput

0.614

High

814357

NOC2
Nucleolar complex protein 2

2

2

High-throughput

0.614

High

800743

RCK1
Serine/threonine-protein kinase RCK1

2

10

High-throughput

0.602

High

924172

RPA49
DNA-directed RNA polymerase I subunit RPA49

2

2

Small-scale

0.601

High

419827

H2A2
Histone H2A.2

2

20

Small-scale

0.595

High

432656

RL7A
Large ribosomal subunit protein uL30A

2

6

High-throughput

0.584

High

586478

PCNA
Proliferating cell nuclear antigen

2

3

Small-scale

0.584

High

820932

RL13B
Large ribosomal subunit protein eL13B

2

6

High-throughput

0.584

High

844564

UTP10
U3 small nucleolar RNA-associated protein 10

2

2

High-throughput

0.584

High

924177

RL6A
Large ribosomal subunit protein eL6A

2

3

High-throughput

0.584

High

924187

RRP5
rRNA biogenesis protein RRP5

2

4

High-throughput

0.584

High

924204

YRA1
RNA annealing protein YRA1

2

10

High-throughput

0.584

High

924191

FKBP4
FK506-binding protein 4

2

4

High-throughput

0.576

High

393136

HSP82
ATP-dependent molecular chaperone HSP82

2

7

High-throughput

0.571

High

527355

HSP72
Heat shock protein SSA2

2

14

High-throughput

0.571

High

670982

SIS1
Protein SIS1

2

6

High-throughput

0.571

High

754505

RT05
Small ribosomal subunit protein uS5m

2

3

High-throughput

0.567

High

924185

SEC13
Protein transport protein SEC13

1

11

High-throughput

0.553

High

751450

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

2

High-throughput

0.549

High

700270

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

4

High-throughput

0.541

High

780201

SN114
Pre-mRNA-splicing factor SNU114

1

6

High-throughput

0.541

High

803901

CIC1
Proteasome-interacting protein CIC1

1

3

High-throughput

0.541

High

827571

RLP7
Ribosome biogenesis protein RLP7

1

6

High-throughput

0.541

High

924197

NOP6
Nucleolar protein 6

1

1

High-throughput

0.541

High

924206

UTP12
U3 small nucleolar RNA-associated protein 12

1

16

High-throughput

0.541

High

739713

SPT16
FACT complex subunit SPT16

2

6

Small-scale

0.533

High

704637

SBA1
Co-chaperone protein SBA1

1

1

Small-scale

0.527

High

849997

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

0

High-throughput

0.518

High

479994

PRTB
Cerevisin

1

1

High-throughput

0.515

High

622991

CSK22
Casein kinase II subunit alpha'

1

5

High-throughput

0.515

High

673212

RRP7
Ribosomal RNA-processing protein 7

1

1

High-throughput

0.515

High

809383

STM1
Suppressor protein STM1

1

1

High-throughput

0.515

High

364676

CDK1
Cyclin-dependent kinase 1

1

9

High-throughput

0.501

High

419477

H2A1
Histone H2A.1

1

20

Small-scale

0.501

High

441209

KAPA
cAMP-dependent protein kinase type 1

1

8

High-throughput

0.501

High

444863

SIR3
Regulatory protein SIR3

1

4

Small-scale

0.501

High

448774

SNF1
Carbon catabolite-derepressing protein kinase

1

10

High-throughput

0.501

High

470151

SPS1
Sporulation-specific protein 1

1

17

High-throughput

0.501

High

574726

KSS1
Mitogen-activated protein kinase KSS1

1

6

High-throughput

0.501

High

599387

FUS3
Mitogen-activated protein kinase FUS3

1

5

High-throughput

0.501

High

602588

PHO85
Cyclin-dependent protein kinase PHO85

1

10

High-throughput

0.501

High

646493

RAD53
Serine/threonine-protein kinase RAD53

1

8

High-throughput

0.501

High

651973

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

2

High-throughput

0.501

High

656569

KC11
Casein kinase I homolog 1

1

8

High-throughput

0.501

High

656828

KC12
Casein kinase I homolog 2

1

3

High-throughput

0.501

High

740603

IME2
Meiosis induction protein kinase IME2/SME1

1

9

High-throughput

0.501

High

748886

SWE1
Mitosis inhibitor protein kinase SWE1

1

14

High-throughput

0.501

High

750284

PRP40
Pre-mRNA-processing protein PRP40

1

1

High-throughput

0.501

High

801881

KSP1
Serine/threonine-protein kinase KSP1

1

16

High-throughput

0.501

High

810657

SSN3
Meiotic mRNA stability protein kinase SSN3

1

10

High-throughput

0.501

High

822231

SECU
Securin

1

2

Small-scale

0.501

High

863936

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

10

High-throughput

0.501

High

865520

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

9

High-throughput

0.501

High

917139

ATG1
Serine/threonine-protein kinase ATG1

1

10

High-throughput

0.501

High

924170

MPS1
Serine/threonine-protein kinase MPS1

1

9

High-throughput

0.501

High

924184

SKY1
Serine/threonine-protein kinase SKY1

1

17

High-throughput

0.501

High

924208

SKM1
Serine/threonine-protein kinase SKM1

1

19

High-throughput

0.501

High

828305

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.493

High

865372

GEA1
ARF guanine-nucleotide exchange factor 1

1

0

High-throughput

0.493

High

919593

NOP19
Nucleolar protein 19

1

0

High-throughput

0.493

High

557753

SRS2
ATP-dependent DNA helicase SRS2

1

2

Small-scale

0.481

High

734272

DBF4
DDK kinase regulatory subunit DBF4

1

0

Small-scale

0.480

High

849919

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.480

High

402071

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

6

Small-scale

0.479

High

434062

RL33A
Large ribosomal subunit protein eL33A

1

3

High-throughput

0.479

High

434184

RL36A
Large ribosomal subunit protein eL36A

1

2

High-throughput

0.479

High

434628

RL22A
Large ribosomal subunit protein eL22A

1

2

High-throughput

0.479

High

452590

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

2

High-throughput

0.479

High

453726

PYR1
Multifunctional protein URA2

1

4

High-throughput

0.479

High

455515

PMM
Phosphomannomutase

1

1

High-throughput

0.479

High

488628

RIR2
Ribonucleoside-diphosphate reductase small chain 1

1

2

High-throughput

0.479

High

504344

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.479

High

511252

RL20B
Large ribosomal subunit protein eL20B

1

2

High-throughput

0.479

High

513737

RL2A
Large ribosomal subunit protein uL2A

1

2

High-throughput

0.479

High

514043

RL18B
Large ribosomal subunit protein eL18B

1

2

High-throughput

0.479

High

515299

RL35A
Large ribosomal subunit protein uL29A

1

1

High-throughput

0.479

High

553640

ERF1
Eukaryotic peptide chain release factor subunit 1

1

2

High-throughput

0.479

High

561196

PYRE
Orotate phosphoribosyltransferase 1

1

1

High-throughput

0.479

High

570099

RL3
Large ribosomal subunit protein uL3

1

4

High-throughput

0.479

High

584319

DPOD
DNA polymerase delta catalytic subunit

1

4

Small-scale

0.479

High

585334

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

2

High-throughput

0.479

High

632713

DBP4
ATP-dependent RNA helicase HCA4

1

17

High-throughput

0.479

High

644965

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

3

Small-scale

0.479

High

647812

RFA1
Replication factor A protein 1

1

8

Small-scale

0.479

High

655593

TKT1
Transketolase 1

1

2

High-throughput

0.479

High

677511

KRR1
KRR1 small subunit processome component

1

3

High-throughput

0.479

High

679930

CDC48
Cell division control protein 48

1

7

High-throughput

0.479

High

682929

MSH2
DNA mismatch repair protein MSH2

1

1

Small-scale

0.479

High

688758

RFA2
Replication factor A protein 2

1

5

Small-scale

0.479

High

689094

RL16A
Large ribosomal subunit protein uL13A

1

4

High-throughput

0.479

High

692600

NSR1
Nuclear localization sequence-binding protein

1

9

High-throughput

0.479

High

707829

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

713630

EF1G1
Elongation factor 1-gamma 1

1

5

High-throughput

0.479

High

734294

PYC2
Pyruvate carboxylase 2

1

6

High-throughput

0.479

High

746652

DRS1
ATP-dependent RNA helicase DRS1

1

20

High-throughput

0.479

High

753509

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.479

High

755142

GCN1
eIF-2-alpha kinase activator GCN1

1

6

High-throughput

0.479

High

760317

BMH2
Protein BMH2

1

6

High-throughput

0.479

High

791083

NOP4
Nucleolar protein 4

1

7

High-throughput

0.479

High

795988

NCL1
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase

1

4

High-throughput

0.479

High

796711

RFC5
Replication factor C subunit 5

1

8

Small-scale

0.479

High

800964

RFC3
Replication factor C subunit 3

1

9

Small-scale

0.479

High

801011

RFC1
Replication factor C subunit 1

1

11

Small-scale

0.479

High

802961

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

2

High-throughput

0.479

High

806554

UTP9
U3 small nucleolar RNA-associated protein 9

1

1

High-throughput

0.479

High

807112

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

4

High-throughput

0.479

High

816166

DPO5
rDNA transcriptional regulator POL5

1

3

High-throughput

0.479

High

816877

NUG1
Nuclear GTP-binding protein NUG1

1

4

High-throughput

0.479

High

822963

RFC4
Replication factor C subunit 4

1

10

Small-scale

0.479

High

823135

RFC2
Replication factor C subunit 2

1

9

Small-scale

0.479

High

863862

RL17B
Large ribosomal subunit protein uL22B

1

3

High-throughput

0.479

High

864030

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

Small-scale

0.479

High

874332

HOSC
Homocitrate synthase, cytosolic isozyme

1

2

High-throughput

0.479

High

878746

ASNS2
Asparagine synthetase [glutamine-hydrolyzing] 2

1

3

High-throughput

0.479

High

887757

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

2

High-throughput

0.479

High

915239

ACS2
Acetyl-coenzyme A synthetase 2

1

3

High-throughput

0.479

High

917444

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

11

High-throughput

0.479

High

918315

RL26B
Large ribosomal subunit protein uL24B

1

6

High-throughput

0.479

High

918938

PESC
Pescadillo homolog

1

3

High-throughput

0.479

High

924168

NAT10
RNA cytidine acetyltransferase

1

4

High-throughput

0.479

High

924171

RL34A
Large ribosomal subunit protein eL34A

1

3

High-throughput

0.479

High

924174

CTF4
DNA polymerase alpha-binding protein

1

17

Small-scale

0.479

High

924175

NOP3
Serine/arginine

1

9

High-throughput

0.479

High

924178

UTP6
U3 small nucleolar RNA-associated protein 6

1

1

High-throughput

0.479

High

924179

RL21A
Large ribosomal subunit protein eL21A

1

2

High-throughput

0.479

High

924180

NOG1
Nucleolar GTP-binding protein 1

1

8

High-throughput

0.479

High

924183

HAS1
ATP-dependent RNA helicase HAS1

1

20

High-throughput

0.479

High

924190

MRD1
Multiple RNA-binding domain-containing protein 1

1

9

High-throughput

0.479

High

924192

DBP9
ATP-dependent RNA helicase DBP9

1

18

High-throughput

0.479

High

924194

BFR2
Protein BFR2

1

1

High-throughput

0.479

High

924196

SUB2
ATP-dependent RNA helicase SUB2

1

12

High-throughput

0.479

High

924198

NOP12
Nucleolar protein 12

1

9

High-throughput

0.479

High

924199

BRX1
Ribosome biogenesis protein BRX1

1

7

High-throughput

0.479

High

924201

MDN1
Midasin

1

20

High-throughput

0.479

High

924205

MAK21
Ribosome biogenesis protein MAK21

1

5

High-throughput

0.479

High

924210

RL13A
Large ribosomal subunit protein eL13A

1

6

High-throughput

0.479

High

924211

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

6

High-throughput

0.479

High

849540

GCN20
Protein GCN20

1

7

High-throughput

0.470

High

416826

DNLI1
DNA ligase 1

1

0

Small-scale

0.458

High

521125

PRI1
DNA primase small subunit

1

0

Small-scale

0.458

High

632851

PRI2
DNA primase large subunit

1

0

Small-scale

0.458

High

688809

RFA3
Replication factor A protein 3

1

0

Small-scale

0.458

High

689760

FEN1
Flap endonuclease 1

1

0

Small-scale

0.458

High

790424

GLY1
Low specificity L-threonine aldolase

1

0

High-throughput

0.458

High

793831

DPOA2
DNA polymerase alpha subunit B

1

0

Small-scale

0.458

High

807641

MLH1
DNA mismatch repair protein MLH1

1

0

Small-scale

0.458

High

849626

SWP82
SWI/SNF global transcription activator complex subunit SWP82

1

0

High-throughput

0.458

High

858238

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

0

Small-scale

0.458

High

863239

DPOD2
DNA polymerase delta small subunit

1

0

Small-scale

0.458

High

924169

RNH2A
Ribonuclease H2 subunit A

1

0

Small-scale

0.458

High

924182

YMY9
Glucose-6-phosphate 1-epimerase

1

0

High-throughput

0.458

High

924188

RNH2B
Ribonuclease H2 subunit B

1

0

Small-scale

0.458

High

924200

ETT1
Enhancer of translation termination 1

1

0

High-throughput

0.458

High

924203

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

560742

KIN2
Serine/threonine-protein kinase KIN2

1

14

High-throughput

0.457

High

692416

KCC1
Calcium/calmodulin-dependent protein kinase I

1

2

High-throughput

0.457

High

825418

PRK1
Actin-regulating kinase PRK1

1

8

High-throughput

0.457

High

850957

TOS3
Serine/threonine-protein kinase TOS3

1

4

High-throughput

0.457

High

918394

FMP48
Probable serine/threonine-protein kinase FMP48

1

12

High-throughput

0.457

High

924173

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

6

High-throughput

0.457

High

924202

YP150
Putative serine/threonine-protein kinase YPL150W

1

10

High-throughput

0.457

High

481714

HSP73
Heat shock protein SSA3

1

14

High-throughput

0.445

High

524765

HSP71
Heat shock protein SSA1

1

14

High-throughput

0.445

High

545809

SSB1
Ribosome-associated molecular chaperone SSB1

1

13

High-throughput

0.445

High

590692

HSP26
Heat shock protein 26

1

1

High-throughput

0.445

High

742120

HSP7F
Heat shock protein homolog SSE1

1

19

High-throughput

0.445

High

742917

HSP79
Heat shock protein homolog SSE2

1

19

High-throughput

0.445

High

804355

SSZ1
Ribosome-associated complex subunit SSZ1

1

8

High-throughput

0.445

High

811366

CAJ1
Protein CAJ1

1

8

High-throughput

0.445

High

819430

SSB2
Ribosome-associated molecular chaperone SSB2

1

13

High-throughput

0.445

High

427391

RLA0
Large ribosomal subunit protein uL10

1

6

High-throughput

0.437

High

458599

SEC4
Ras-related protein SEC4

1

2

High-throughput

0.437

High

561322

DPOLA
DNA polymerase alpha catalytic subunit A

1

4

Small-scale

0.437

High

661673

MPCP
Mitochondrial phosphate carrier protein

1

1

High-throughput

0.437

High

701728

URA7
CTP synthase 1

1

2

High-throughput

0.437

High

795135

NU170
Nucleoporin NUP170

1

3

High-throughput

0.437

High

893141

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

3

High-throughput

0.437

High

924186

POB3
FACT complex subunit POB3

1

2

Small-scale

0.437

High

924176

UBC7
Ubiquitin-conjugating enzyme E2 7

1

8

High-throughput

0.417

High

510706

HSP77
Import motor subunit, mitochondrial

1

15

High-throughput

0.407

High

577189

SEC63
Protein translocation protein SEC63

1

7

High-throughput

0.407

High

752579

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.407

High

816346

HSP7E
Heat shock protein SSC3, mitochondrial

1

15

High-throughput

0.407

High

850642

ERJ5
ER-localized J domain-containing protein 5

1

7

High-throughput

0.407

High

917935

PDK2
[Pyruvate dehydrogenase

1

0

High-throughput

0.261

Low

737359

DPH5
Diphthine methyl ester synthase

1

0

High-throughput

0.249

Low

748489

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

784003

RM10
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.249

Low

805263

SBE22
Protein SBE22

1

0

High-throughput

0.249

Low

835947

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025