Interactor 1: PSB6 (P28072)
Proteasome subunit beta type-6 (EC 3.4.25.1) (Macropain delta chain) (Multicatalytic endopeptidase complex delta chain) (Proteasome delta chain) (Proteasome subunit Y)
Gene: PSMB6

Interactor 2: PSB3 (P49720)
Proteasome subunit beta type-3 (Proteasome chain 13) (Proteasome component C10-II) (Proteasome theta chain)
Gene: PSMB3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.863

The method score is based on:

Property Details
Experiments 28514442, 33961781, 17948026
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 4 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 239
Hs

1 205
+ Dm
+ Dm
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Ph
+ Hs
+ Sp
+ Dm
+ Dm
+ Sp
+ Mm
+ Dm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024