HitPredict

Interactor 1: PTPRB (P23467)
Receptor-type tyrosine-protein phosphatase beta (Protein-tyrosine phosphatase beta) (R-PTP-beta) (EC 3.1.3.48) (Vascular endothelial protein tyrosine phosphatase) (VE-PTP)
Gene: PTPRB

Interactor 2: NRCAM (Q92823)
Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (hBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related)
Gene: NRCAM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	9049255
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	fn3~fn3, I-set~fn3, Ig_3~fn3, Y_phosphatase~fn3
Common GO terms	GO:0001525 - angiogenesis GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1997 Hs			1 1304
+	Hs
		658820 PTPRB_HUMAN (1-1997): 0: 1308: 100.00		CNTN1_HUMAN (4-944): 3.07e-97: 337: 15.62
+	Gg
		47687 A0A8V0YWD3_CHICK (1687-1966): 1.61e-103: 356: 35.23		CNTN1_CHICK (340-1181): 3.11e-75: 273: 14.86
+	Mm
		1424402 DSCAM_MOUSE (2-661): 4.09e-64: 244: 13.56		DSCAM_MOUSE (3-1164): 8.66e-107: 375: 15.86
+	Hs
		139374 PTPRA_HUMAN (1687-1966): 2.18e-103: 353: 35.23		NCHL1_HUMAN (638-1143): 9.42e-20: 98.3: 10.53
+	Hs
		659080 PTPRZ_HUMAN (1703-1976): 2.11e-23: 111: 30.96		CNTN1_HUMAN (4-944): 3.07e-97: 337: 15.62
+	Hs
		389455 FINC_HUMAN (615-1720): 1.42e-94: 344: 14.47		TITIN_HUMAN (946-1174): 1.77e-10: 68.2: 9.61
+	Mm
		611450 PTPRA_MOUSE (1683-1966): 1.23e-48: 190: 35.29		NCHL1_MOUSE (2-730): 1.78e-47: 188: 14.88
+	Mm
		1190058 SDK1_MOUSE (4-212): 3.92e-19: 97.4: 15.79		SDK1_MOUSE (130-1299): 3.47e-75: 278: 16.22
+	Mm
		999933 DSCAM_MOUSE (2-661): 4.09e-64: 244: 13.56		DCC_MOUSE (662-1181): 1.37e-25: 117: 10.67
+	Mm
		1250401 DSCAM_MOUSE (2-661): 4.09e-64: 244: 13.56		SDK2_MOUSE (736-1178): 1.34e-18: 94.8: 9.87
+	Mm
		98425 DSCAM_MOUSE (2-661): 4.09e-64: 244: 13.56		E9QPR7_MOUSE (4-379): 7.42e-15: 82.5: 11.64
+	Dr
		47644 A0A8M1RL98_DANRE (1685-1979): 2.54e-22: 107: 27.36		A4JYP8_DANRE (455-1168): 1.72e-46: 184: 13.48
+	Dr
		62665 B8A5J4_DANRE (1716-1979): 3.93e-22: 106: 28.57		A4JYP8_DANRE (455-1168): 1.72e-46: 184: 13.48
+	Mm
		1250400 SDK2_MOUSE (829-1770): 6.57e-38: 159: 9.17		SDK2_MOUSE (736-1178): 1.34e-18: 94.8: 9.87
+	Mm
		98424 SDK2_MOUSE (829-1770): 6.57e-38: 159: 9.17		E9QPR7_MOUSE (4-379): 7.42e-15: 82.5: 11.64
+	Hs
		1361883 TITIN_HUMAN (225-490): 8.68e-09: 63.5: 8.27		NEO1_HUMAN (354-1143): 8.37e-25: 114: 23.14
+	Hs
		1361879 TITIN_HUMAN (225-490): 8.68e-09: 63.5: 8.27		TITIN_HUMAN (946-1174): 1.77e-10: 68.2: 9.61