Interactor 1: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Interactor 2: TITIN (Q8WZ42)
Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)
Gene: TTN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 22778266
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~fn3, I-set~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005576 - extracellular region
GO:0005829 - cytosol
GO:0106310 - protein serine kinase activity
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 360
Hs

1 34350
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024