HitPredict

Interactor 1: RBL1 (P28749)
Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1)
Gene: RBL1

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.641

The method score is based on:

Property Details
Experiments 10490602, 9724731
Identification Methods affinity chromatography technology, pull down, coimmunoprecipitation, biochemical
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0005654 - nucleoplasm
GO:0006325 - chromatin organization
GO:0010629 - negative regulation of gene expression
and 1 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1068
Hs

1 482
+ Hs
+ Hs
+ Mm
+ Rn
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Hs
+ Ce
+ Dm

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Last updated: 15 Jul 2024