HitPredict

Interactor 1: GRIA1 (P23818)
Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (GluA1)
Gene: GRIA1

Interactor 2: GRIA2 (P23819)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.956

The method score is based on:

Property Details
Experiments 36417873, 25456134, 29515177, 14561864, 14687553, 15883194, 19022416, 16601687
Identification Methods proximity labelling technology, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan-Glu_bd~Lig_chan-Glu_bd
Common GO terms GO:0004970 - glutamate-gated receptor activity
GO:0004971 - AMPA glutamate receptor activity
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0007268 - chemical synaptic transmission
and 15 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 907
Mm

1 883
+ Rn
+ Hs
+ Mm
+ Rn
+ Hs
+ Rn
+ Mm
+ Hs
+ Rn
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm

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Last updated: 11Aug2025