HitPredict

Interactor 1: ZBT25 (P24278)
Zinc finger and BTB domain-containing protein 25 (Zinc finger protein 46) (Zinc finger protein KUP)
Gene: ZBTB25

Interactor 2: ZBT25 (P24278)
Zinc finger and BTB domain-containing protein 25 (Zinc finger protein 46) (Zinc finger protein KUP)
Gene: ZBTB25

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.815

The method score is based on:

Property Details
Experiments 25416956, 20211142
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BTB~BTB, zf-C2H2~zf-C2H2
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001817 - regulation of cytokine production
GO:0002682 - regulation of immune system process
and 3 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 435
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1 435
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Service provided by Combinatics, Japan

Last updated: 11Aug2025