HitPredict

Interactor 1: EPHB2 (P29323)
Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]
Gene: EPHB2

Interactor 2: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030425 - dendrite
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1055 Hs			1 2221
+	Hs
		872613 EPHB1_HUMAN (20-985): 0: 1211: 73.60		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		1047091 EPHA7_HUMAN (6-982): 0: 1154: 57.46		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		665395 EPHA3_HUMAN (16-980): 0: 1152: 56.37		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		872644 EPHA4_HUMAN (6-982): 0: 1152: 58.33		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		872439 EPHA5_HUMAN (6-984): 0: 1148: 56.69		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		1047303 EPHA6_HUMAN (16-983): 0: 1111: 52.32		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		665475 EPHA8_HUMAN (20-982): 0: 1066: 50.71		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		872476 EPHA5_HUMAN (6-984): 0: 1148: 56.69		SCN2A_HUMAN (1221-1548): 8.66e-16: 86.5: 16.45