Interactor 1: PTN6 (P29350)
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Protein-tyrosine phosphatase SHP-1) (SH-PTP1)
Gene: PTPN6

Interactor 2: PTN6 (P29350)
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Protein-tyrosine phosphatase SHP-1) (SH-PTP1)
Gene: PTPN6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 27432908, 31980649
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, SH2~Y_phosphatase, Y_phosphatase~Y_phosphatase
Common GO terms GO:0000165 - MAPK cascade
GO:0000278 - mitotic cell cycle
GO:0001784 - phosphotyrosine residue binding
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0002924 - negative regulation of humoral immune response mediated by circulating immunoglobulin
and 55 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 595
Hs

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Last updated: 15 Jul 2024