HitPredict

Interactor 1: PTN6 (P29350)
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Protein-tyrosine phosphatase SHP-1) (SH-PTP1)
Gene: PTPN6

Interactor 2: SIGL9 (Q9Y336)
Sialic acid-binding Ig-like lectin 9 (Siglec-9) (CDw329) (Protein FOAP-9) (CD antigen CD329)
Gene: SIGLEC9

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.585

Property	Details
Experiments	15703304, 10887109, 15292262
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 463
+	Hs
		665970 PTN6_HUMAN (1-595): 0: 628: 100.00		SIGL7_HUMAN (20-463): 5.28e-84: 268: 75.33
+	Hs
		177594 PTN6_HUMAN (1-595): 0: 628: 100.00		SIGL5_HUMAN (34-463): 1.35e-25: 111: 17.76
+	Hs
		665942 PTN6_HUMAN (1-595): 0: 628: 100.00		SIG11_HUMAN (73-462): 9.19e-25: 109: 21.04
+	Hs
		589559 PTN6_HUMAN (1-595): 0: 628: 100.00		CD33_HUMAN (140-461): 2.13e-24: 105: 19.22
+	Hs
		665940 PTN6_HUMAN (1-595): 0: 628: 100.00		SIG10_HUMAN (42-460): 5.38e-22: 101: 15.56
+	Hs
		590601 PTN6_HUMAN (1-595): 0: 628: 100.00		CD22_HUMAN (20-351): 3.41e-20: 95.8: 14.37
+	Mm
		665976 PTN6_MOUSE (1-595): 0: 611: 94.45		CD22_MOUSE (8-351): 1.81e-24: 108: 16.29
+	Hs
		663990 PTN4_HUMAN (78-519): 2.47e-122: 385: 27.61		CADM1_HUMAN (10-339): 2.31e-53: 187: 16.52
+	Mm
		682309 PTN12_MOUSE (218-575): 3.21e-115: 362: 32.42		CEAM1_MOUSE (60-368): 2.72e-28: 119: 15.56
+	Hs
		581462 PTN4_HUMAN (78-519): 2.47e-122: 385: 27.61		VCAM1_HUMAN (103-341): 2.93e-17: 86.4: 20.16
+	Mm
		1143580 PTPRR_MOUSE (13-515): 7.09e-122: 376: 26.74		Q8BG33_MOUSE (152-428): 1.29e-18: 88.6: 13.59
+	Hs
		68228 PTPRS_HUMAN (108-516): 3.34e-114: 376: 27.93		HECA2_HUMAN (7-368): 1.05e-15: 81: 18.73
+	Hs
		68222 PTPRF_HUMAN (93-516): 1.07e-112: 372: 26.98		HECA2_HUMAN (7-368): 1.05e-15: 81: 18.73
+	Hs
		1069952 PTPRK_HUMAN (72-519): 3.22e-71: 251: 21.06		PXDN_HUMAN (118-462): 2.71e-44: 168: 14.85
+	Hs
		441175 PTPRC_HUMAN (118-575): 2.27e-82: 283: 20.20		CD22_HUMAN (20-351): 3.41e-20: 95.8: 14.37
+	Hs
		1069962 PTPRK_HUMAN (72-519): 3.22e-71: 251: 21.06		LRIG1_HUMAN (230-443): 1.96e-21: 99.8: 11.30
+	Hs
		545101 PTN11_HUMAN (2-203): 1.25e-24: 110: 25.23		PVR_HUMAN (14-407): 2.63e-56: 193: 18.77
+	Hs
		177596 PTN11_HUMAN (2-203): 1.25e-24: 110: 25.23		SIGL5_HUMAN (34-463): 1.35e-25: 111: 17.76
+	Hs
		589567 PTN11_HUMAN (2-203): 1.25e-24: 110: 25.23		CD33_HUMAN (140-461): 2.13e-24: 105: 19.22
+	Hs
		581691 PTN11_HUMAN (2-203): 1.25e-24: 110: 25.23		VCAM1_HUMAN (103-341): 2.93e-17: 86.4: 20.16