HitPredict

Interactor 1: CCNC (P24863)
Cyclin-C (SRB11 homolog) (hSRB11)
Gene: CCNC

Interactor 2: MD13L (Q71F56)
Mediator of RNA polymerase II transcription subunit 13-like (Mediator complex subunit 13-like) (Thyroid hormone receptor-associated protein 2) (Thyroid hormone receptor-associated protein complex 240 kDa component-like)
Gene: MED13L

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.729

Property	Details
Experiments	26186194, 28514442, 33961781, 24981860, 36950384, unassigned3799
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0016592 - mediator complex GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 283 Hs			1 2210
+	Hs
		95748 E5RFK5_HUMAN (1-257): 8.37e-74: 229: 100.00		MD13L_HUMAN (1-2210): 0: 3763: 100.00
+	Hs
		666925 CCNC_HUMAN (1-283): 1.06e-79: 244: 100.00		MED13_HUMAN (4-2210): 0: 3181: 51.34
+	Hs
		95764 E5RFK5_HUMAN (1-257): 8.37e-74: 229: 100.00		MED13_HUMAN (4-2210): 0: 3181: 51.34
+	Dm
		668159 CCNC_DROME (1-256): 2.01e-75: 232: 71.60		MED13_DROME (943-1152): 8.66e-10: 66.7: 23.77