Protein: CCNC
Cyclin-C (SRB11 homolog) (hSRB11)

Gene: CCNC
Organism: Homo sapiens
Interactions: 201
UniProt ID: P24863

Gene Ontology (top 5):
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016538 - cyclin-dependent protein serine/threonine kinase regulator activity
GO:0016592 - mediator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

666811

CDK8
Cyclin-dependent kinase 8

27

20

Small-scale

0.993

High

666903

CDK19
Cyclin-dependent kinase 19

10

20

Small-scale

0.972

High

666822

CDK3
Cyclin-dependent kinase 3

4

20

Small-scale

0.894

High

666795

CCNC
Cyclin-C

2

11

High-throughput

0.783

High

666899

MED10
Mediator of RNA polymerase II transcription subunit 10

9

2

Small-scale

0.751

High

48906

MED19
Mediator of RNA polymerase II transcription subunit 19

8

1

Small-scale

0.749

High

666909

MED28
Mediator of RNA polymerase II transcription subunit 28

8

1

High-throughput

0.746

High

666915

MED4
Mediator of RNA polymerase II transcription subunit 4

7

1

High-throughput

0.745

High

666920

MED29
Mediator of RNA polymerase II transcription subunit 29

7

2

High-throughput

0.745

High

666835

MED1
Mediator of RNA polymerase II transcription subunit 1

8

5

Small-scale

0.744

High

287764

MED6
Mediator of RNA polymerase II transcription subunit 6

7

2

Small-scale

0.741

High

666880

MED12
Mediator of RNA polymerase II transcription subunit 12

7

6

Small-scale

0.739

High

666829

MED21
Mediator of RNA polymerase II transcription subunit 21

6

1

High-throughput

0.732

High

239538

MED14
Mediator of RNA polymerase II transcription subunit 14

6

12

High-throughput

0.729

High

666834

MED22
Mediator of RNA polymerase II transcription subunit 22

6

1

High-throughput

0.729

High

666848

MED27
Mediator of RNA polymerase II transcription subunit 27

6

1

High-throughput

0.729

High

666857

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

6

4

High-throughput

0.729

High

666900

MED18
Mediator of RNA polymerase II transcription subunit 18

6

1

High-throughput

0.729

High

666911

MED20
Mediator of RNA polymerase II transcription subunit 20

6

1

High-throughput

0.729

High

666925

MED13
Mediator of RNA polymerase II transcription subunit 13

6

5

High-throughput

0.727

High

666931

MED23
Mediator of RNA polymerase II transcription subunit 23

6

1

High-throughput

0.724

High

666937

MED31
Mediator of RNA polymerase II transcription subunit 31

5

1

High-throughput

0.718

High

666919

MED9
Mediator of RNA polymerase II transcription subunit 9

5

1

High-throughput

0.712

High

282354

MED24
Mediator of RNA polymerase II transcription subunit 24

5

1

High-throughput

0.706

High

666885

MED8
Mediator of RNA polymerase II transcription subunit 8

5

1

High-throughput

0.706

High

666893

MED15
Mediator of RNA polymerase II transcription subunit 15

5

6

High-throughput

0.706

High

666918

MED17
Mediator of RNA polymerase II transcription subunit 17

5

1

High-throughput

0.706

High

666935

MED16
Mediator of RNA polymerase II transcription subunit 16

5

1

High-throughput

0.706

High

219471

MED7
Mediator of RNA polymerase II transcription subunit 7

4

3

High-throughput

0.694

High

666923

MED11
Mediator of RNA polymerase II transcription subunit 11

4

1

High-throughput

0.694

High

666815

CCNH
Cyclin-H

1

10

Small-scale

0.692

High

666863

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

4

12

High-throughput

0.686

High

666894

MINT
Msx2-interacting protein

4

9

High-throughput

0.683

High

666858

MED25
Mediator of RNA polymerase II transcription subunit 25

4

0

High-throughput

0.661

High

395510

ESR1
Estrogen receptor

3

19

Small-scale

0.660

High

666882

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

2

1

High-throughput

0.644

High

600041

ZNF18
Zinc finger protein 18

3

0

High-throughput

0.643

High

666886

MED30
Mediator of RNA polymerase II transcription subunit 30

3

0

High-throughput

0.638

High

666814

MEOX2
Homeobox protein MOX-2

2

2

High-throughput

0.633

High

209951

CRX
Cone-rod homeobox protein

2

1

High-throughput

0.628

High

666913

TRI39
E3 ubiquitin-protein ligase TRIM39

2

2

High-throughput

0.628

High

666823

CDK5
Cyclin-dependent kinase 5

1

20

High-throughput

0.618

High

666832

K1H1
Keratin, type I cuticular Ha1

3

7

High-throughput

0.616

High

335957

MED26
Mediator of RNA polymerase II transcription subunit 26

2

2

High-throughput

0.611

High

666821

NGAL
Neutrophil gelatinase-associated lipocalin

3

1

High-throughput

0.607

High

476270

K1C16
Keratin, type I cytoskeletal 16

2

8

High-throughput

0.606

High

505692

ZN688
Zinc finger protein 688

2

1

High-throughput

0.606

High

587943

RFA2
Replication protein A 32 kDa subunit

2

8

High-throughput

0.606

High

666805

VHL
von Hippel-Lindau disease tumor suppressor

2

1

High-throughput

0.606

High

666807

CDN2B
Cyclin-dependent kinase 4 inhibitor B

2

6

High-throughput

0.606

High

666818

CKS1
Cyclin-dependent kinases regulatory subunit 1

2

20

High-throughput

0.606

High

666819

UBE2K
Ubiquitin-conjugating enzyme E2 K

2

4

High-throughput

0.606

High

666820

PO6F2
POU domain, class 6, transcription factor 2

2

2

High-throughput

0.606

High

666824

PAX5
Paired box protein Pax-5

2

1

High-throughput

0.606

High

666825

REL
Proto-oncogene c-Rel

2

4

High-throughput

0.606

High

666868

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

5

High-throughput

0.606

High

666871

CCHCR
Coiled-coil alpha-helical rod protein 1

2

1

High-throughput

0.606

High

666901

ZN426
Zinc finger protein 426

2

1

High-throughput

0.606

High

666891

PNMA5
Paraneoplastic antigen-like protein 5

2

0

High-throughput

0.601

High

666912

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

2

0

High-throughput

0.601

High

442592

RB
Retinoblastoma-associated protein

1

12

Small-scale

0.589

High

259457

BRD4
Bromodomain-containing protein 4

2

16

High-throughput

0.584

High

352076

MBD3
Methyl-CpG-binding domain protein 3

2

0

High-throughput

0.580

High

666806

RFC5
Replication factor C subunit 5

2

0

High-throughput

0.580

High

666838

F161A
Protein FAM161A

2

0

High-throughput

0.580

High

666839

ZN792
Zinc finger protein 792

2

0

High-throughput

0.580

High

666850

FOXR2
Forkhead box protein R2

2

0

High-throughput

0.580

High

666851

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

2

0

High-throughput

0.580

High

666853

ZN620
Zinc finger protein 620

2

0

High-throughput

0.580

High

666870

G45IP
Large ribosomal subunit protein mL64

2

0

High-throughput

0.580

High

666873

ZFP90
Zinc finger protein 90 homolog

2

0

High-throughput

0.580

High

666884

NRBF2
Nuclear receptor-binding factor 2

2

0

High-throughput

0.580

High

666895

PRP18
Pre-mRNA-splicing factor 18

2

0

High-throughput

0.580

High

666896

SPAG8
Sperm-associated antigen 8

2

0

High-throughput

0.580

High

666902

RUSC1
AP-4 complex accessory subunit RUSC1

2

0

High-throughput

0.580

High

666914

VTA1
Vacuolar protein sorting-associated protein VTA1 homolog

2

0

High-throughput

0.580

High

666924

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

2

0

High-throughput

0.580

High

666929

SRTD3
SERTA domain-containing protein 3

2

0

High-throughput

0.580

High

666932

ISY1
Pre-mRNA-splicing factor ISY1 homolog

2

0

High-throughput

0.580

High

666934

FA50B
Protein FAM50B

2

0

High-throughput

0.580

High

666865

HACE1
E3 ubiquitin-protein ligase HACE1

1

5

Small-scale

0.578

High

566240

K1C13
Keratin, type I cytoskeletal 13

2

7

High-throughput

0.576

High

190044

FOXP2
Forkhead box protein P2

1

4

High-throughput

0.573

High

617999

K1C15
Keratin, type I cytoskeletal 15

1

6

High-throughput

0.573

High

666926

PUF60
Poly(U)-binding-splicing factor PUF60

1

5

High-throughput

0.573

High

300302

KRT34
Keratin, type I cuticular Ha4

2

7

High-throughput

0.553

High

666859

K1C27
Keratin, type I cytoskeletal 27

2

7

High-throughput

0.553

High

666862

F90A1
Protein FAM90A1

2

1

High-throughput

0.553

High

666877

SHC3
SHC-transforming protein 3

2

6

High-throughput

0.553

High

666887

RBM41
RNA-binding protein 41

2

3

High-throughput

0.553

High

666889

CFA53
Cilia- and flagella-associated protein 53

2

1

High-throughput

0.553

High

666904

BTBD2
BTB/POZ domain-containing protein 2

2

1

High-throughput

0.553

High

666933

T3JAM
TRAF3-interacting JNK-activating modulator

2

3

High-throughput

0.553

High

284798

TADA3
Transcriptional adapter 3

1

0

High-throughput

0.549

High

666840

GLYR1
Cytokine-like nuclear factor N-PAC

1

0

High-throughput

0.549

High

666916

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.549

High

415354

HSPB1
Heat shock protein beta-1

1

3

High-throughput

0.541

High

369440

AACT
Alpha-1-antichymotrypsin

1

6

High-throughput

0.536

High

444902

S10A9
Protein S100-A9

1

6

High-throughput

0.536

High

635563

FILA
Filaggrin

1

4

High-throughput

0.536

High

666798

S100P
Protein S100-P

1

6

High-throughput

0.536

High

666799

SPB3
Serpin B3

1

5

High-throughput

0.536

High

666801

S10A7
Protein S100-A7

1

6

High-throughput

0.536

High

666802

CASPE
Caspase-14

1

2

High-throughput

0.536

High

666842

FILA2
Filaggrin-2

1

4

High-throughput

0.536

High

666849

FXL19
F-box/LRR-repeat protein 19

1

5

High-throughput

0.536

High

666928

SPB13
Serpin B13

1

5

High-throughput

0.536

High

666827

GOGA2
Golgin subfamily A member 2

1

2

High-throughput

0.523

High

666897

LZTS2
Leucine zipper putative tumor suppressor 2

1

3

High-throughput

0.523

High

280509

PR40A
Pre-mRNA-processing factor 40 homolog A

1

7

High-throughput

0.515

High

666817

CASP6
Caspase-6

1

2

High-throughput

0.515

High

666847

Q6FHY5
MEOX2 protein

1

2

High-throughput

0.515

High

666854

SRCAP
Helicase SRCAP

1

2

High-throughput

0.515

High

126225

ST2B1
Sulfotransferase 2B1

1

0

High-throughput

0.513

High

567739

HEM2
Delta-aminolevulinic acid dehydratase

1

0

High-throughput

0.513

High

578636

GLNA
Glutamine synthetase

1

0

High-throughput

0.513

High

582544

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.513

High

659129

LORI
Loricrin

1

0

High-throughput

0.513

High

666797

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.513

High

666809

LEG7
Galectin-7

1

0

High-throughput

0.513

High

666907

ZN350
Zinc finger protein 350

1

0

High-throughput

0.513

High

666921

IL37
Interleukin-37

1

0

High-throughput

0.513

High

622753

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

4

Small-scale

0.501

High

666812

MCM2
DNA replication licensing factor MCM2

1

6

Small-scale

0.501

High

666878

ESR2
Estrogen receptor beta

1

19

Small-scale

0.501

High

590381

GATA1
Erythroid transcription factor

1

1

Small-scale

0.500

High

666808

HD
Huntingtin

1

0

High-throughput

0.493

High

666860

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

666879

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

210712

KLK10
Kallikrein-10

1

2

High-throughput

0.489

High

261600

CATL2
Cathepsin L2

1

1

High-throughput

0.489

High

289240

SPB7
Serpin B7

1

6

High-throughput

0.489

High

423739

APOD
Apolipoprotein D

1

1

High-throughput

0.489

High

485778

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

1

1

High-throughput

0.489

High

652277

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

1

High-throughput

0.489

High

666810

SPB4
Serpin B4

1

5

High-throughput

0.489

High

666813

KLK7
Kallikrein-7

1

1

High-throughput

0.489

High

666826

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.489

High

666861

S1A7A
Protein S100-A7A

1

6

High-throughput

0.489

High

666864

SPA12
Serpin A12

1

6

High-throughput

0.489

High

666866

FAM9C
Protein FAM9C

1

1

High-throughput

0.489

High

666930

DJC12
DnaJ homolog subfamily C member 12

1

3

High-throughput

0.489

High

283657

GPC4
Glypican-4

1

0

High-throughput

0.486

High

666910

P63
Tumor protein 63

1

9

High-throughput

0.481

High

240783

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.479

High

621556

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

666796

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

5

High-throughput

0.479

High

666800

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.479

High

666803

T2FA
General transcription factor IIF subunit 1

1

1

Small-scale

0.479

High

666804

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

3

High-throughput

0.479

High

666828

TP53B
TP53-binding protein 1

1

3

High-throughput

0.479

High

666830

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

7

Small-scale

0.479

High

666844

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

3

High-throughput

0.479

High

666881

FBXW7
F-box/WD repeat-containing protein 7

1

3

Small-scale

0.479

High

49883

A1A4E9
Keratin 13

1

7

High-throughput

0.470

High

116853

I6L9F6
NEFL protein

1

4

High-throughput

0.470

High

561901

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.470

High

570358

GFAP
Glial fibrillary acidic protein

1

3

High-throughput

0.470

High

666841

GLE1
mRNA export factor GLE1

1

2

High-throughput

0.470

High

666888

MY15B
Unconventional myosin-XVB

1

1

High-throughput

0.470

High

666936

SHLB1
Endophilin-B1

1

3

High-throughput

0.470

High

621812

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.458

High

666816

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.458

High

666831

IRF4
Interferon regulatory factor 4

1

0

Small-scale

0.458

High

666856

ACD11
Acyl-CoA dehydrogenase family member 11

1

0

High-throughput

0.458

High

451123

NFL
Neurofilament light polypeptide

1

4

High-throughput

0.439

High

666906

TRI54
Tripartite motif-containing protein 54

1

10

High-throughput

0.439

High

155078

SOCS2
Suppressor of cytokine signaling 2

1

8

Small-scale

0.437

High

666876

LZIC
Protein LZIC

1

1

High-throughput

0.437

High

666883

MTBP
Mdm2-binding protein

1

1

Small-scale

0.437

High

666917

CISH
Cytokine-inducible SH2-containing protein

1

7

Small-scale

0.437

High

622122

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

4

0

High-throughput

0.363

High

253053

PLIN3
Perilipin-3

2

0

High-throughput

0.316

High

605437

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

2

0

High-throughput

0.316

High

666867

RIBC1
RIB43A-like with coiled-coils protein 1

2

0

High-throughput

0.316

High

666872

PKHO2
Pleckstrin homology domain-containing family O member 2

2

0

High-throughput

0.316

High

666890

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.316

High

666905

TEX12
Testis-expressed protein 12

2

0

High-throughput

0.316

High

166864

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.299

High

666875

DYDC1
DPY30 domain-containing protein 1

1

0

High-throughput

0.299

High

276566

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

0

High-throughput

0.279

Low

609294

SAP3
Ganglioside GM2 activator

1

0

High-throughput

0.279

Low

627109

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.279

Low

665912

IBP6
Insulin-like growth factor-binding protein 6

1

0

High-throughput

0.279

Low

666833

CDSN
Corneodesmosin

1

0

High-throughput

0.279

Low

666836

CH3L2
Chitinase-3-like protein 2

1

0

High-throughput

0.279

Low

666837

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.279

Low

666843

XKR4
XK-related protein 4

1

0

High-throughput

0.279

Low

666845

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.279

Low

666846

DMKN
Dermokine

1

0

High-throughput

0.279

Low

666852

SBSN
Suprabasin

1

0

High-throughput

0.279

Low

666855

FBX50
F-box only protein 50

1

0

High-throughput

0.279

Low

666869

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

0

High-throughput

0.279

Low

666874

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

666892

GSDMA
Gasdermin-A

1

0

High-throughput

0.279

Low

666908

RNAS7
Ribonuclease 7

1

0

High-throughput

0.279

Low

666922

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.279

Low

666927

CBPA4
Carboxypeptidase A4

1

0

High-throughput

0.279

Low

47307

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

666898

UBAC1
Ubiquitin-associated domain-containing protein 1

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025