HitPredict

Interactor 1: RPB1 (P24928)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A

Interactor 2: AFF1 (P51825)
AF4/FMR2 family member 1 (ALL1-fused gene from chromosome 4 protein) (Protein AF-4) (Protein FEL) (Proto-oncogene AF4)
Gene: AFF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	21030982
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1970 Hs			1 1210
+	Hs
		667417 RPB1_HUMAN (1-1611): 0: 1900: 100.00		CIC_HUMAN (222-1000): 3.42e-13: 77: 8.22
+	Hs
		667305 RPB1_HUMAN (1-1611): 0: 1900: 100.00		MDC1_HUMAN (84-869): 9.51e-12: 72: 15.09
+	Hs
		161411 RPB1_HUMAN (1-1611): 0: 1900: 100.00		KMT2D_HUMAN (23-1021): 4.87e-11: 69.7: 10.24
+	Hs
		165077 RPC1_HUMAN (16-1484): 0: 1348: 33.09		CIC_HUMAN (222-1000): 3.42e-13: 77: 8.22
+	Dm
		402281 RPB1_DROME (1692-1966): 1.58e-11: 72.3: 39.80		Q9VLS7_DROME (104-1104): 2.4e-14: 80.5: 8.15