HitPredict

Interactor 1: MCM2 (P29469)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2)
Gene: MCM2

Interactor 2: DBF4 (P32325)
DDK kinase regulatory subunit DBF4 (Dumbbell forming protein 4)
Gene: DBF4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.749

Property	Details
Experiments	9407029, 23499444, 34963704, 16107698, 23549044, 19692334, 20436286
Identification Methods	two hybrid, affinity chromatography technology, x-ray crystallography, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003688 - DNA replication origin binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006279 - premeiotic DNA replication
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 868 Sc			1 704
+	Sc
		675508 MCM4_YEAST (38-851): 0: 672: 25.54		DBF4_YEAST (1-704): 0: 1263: 100.00
+	Sc
		622149 MCM3_YEAST (305-833): 2.8e-87: 300: 37.65		DBF4_YEAST (1-704): 0: 1263: 100.00
+	Sc
		667835 MCM5_YEAST (207-848): 1.04e-85: 291: 32.24		DBF4_YEAST (1-704): 0: 1263: 100.00