HitPredict

Interactor 1: MCM5 (P29496)
Minichromosome maintenance protein 5 (EC 3.6.4.12) (Cell division control protein 46)
Gene: MCM5

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0031298 - replication fork protection complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 775 Sc			1 136
+	Hs
		708603 MCM5_HUMAN (3-772): 0: 760: 46.21		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		708605 MCM5_HUMAN (3-772): 0: 760: 46.21		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		708661 MCM5_HUMAN (3-772): 0: 760: 46.21		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Hs
		708690 MCM5_HUMAN (3-772): 0: 760: 46.21		H32_HUMAN (1-136): 6.6e-61: 185: 88.97
+	Hs
		708677 MCM5_HUMAN (3-772): 0: 760: 46.21		H37_HUMAN (1-136): 6.09e-59: 180: 86.77
+	Hs
		708683 MCM5_HUMAN (3-772): 0: 760: 46.21		H3C_HUMAN (1-136): 8.2e-59: 179: 86.03
+	Hs
		832357 MCM2_HUMAN (2-774): 0: 675: 27.72		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		832369 MCM2_HUMAN (2-774): 0: 675: 27.72		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		832495 MCM2_HUMAN (2-774): 0: 675: 27.72		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Hs
		832541 MCM2_HUMAN (2-774): 0: 675: 27.72		H32_HUMAN (1-136): 6.6e-61: 185: 88.97
+	Mm
		935446 MCM2_MOUSE (2-774): 0: 668: 27.60		H31_MOUSE (1-136): 3.24e-62: 188: 88.97
+	Mm
		952736 MCM2_MOUSE (2-774): 0: 668: 27.60		H33_MOUSE (1-136): 1.25e-61: 187: 90.44
+	Mm
		952250 MCM2_MOUSE (2-774): 0: 668: 27.60		H32_MOUSE (1-136): 6.6e-61: 185: 88.97
+	Mm
		935447 MCM6_MOUSE (5-767): 0: 652: 26.86		H31_MOUSE (1-136): 3.24e-62: 188: 88.97
+	Mm
		952737 MCM6_MOUSE (5-767): 0: 652: 26.86		H33_MOUSE (1-136): 1.25e-61: 187: 90.44
+	Mm
		952251 MCM6_MOUSE (5-767): 0: 652: 26.86		H32_MOUSE (1-136): 6.6e-61: 185: 88.97
+	Mm
		935450 Q3V122_MOUSE (23-770): 0: 648: 27.07		H31_MOUSE (1-136): 3.24e-62: 188: 88.97
+	Sc
		675545 MCM4_YEAST (19-747): 0: 659: 28.05		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Hs
		828172 MCM2_HUMAN (2-774): 0: 675: 27.72		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Sc
		675521 MCM4_YEAST (19-747): 0: 659: 28.05		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04