Protein: E2F1
Transcription factor E2f1 (dE2F)

Gene: E2F1
Organism: Drosophila melanogaster
Interactions: 28
UniProt ID: Q27368

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1173502

TFDP
Transcription factor Dp

5

20

Small-scale

0.899

High

1174310

RBF
Retinoblastoma family protein

12

20

Small-scale

0.754

High

1176453

Q9VDE3
LD08669p

1

4

Small-scale

0.561

High

715249

ETS3
DNA-binding protein D-ETS-3

1

5

High-throughput

0.541

High

1176447

SUZ12
Polycomb protein Su(z)12

1

2

High-throughput

0.541

High

1028574

ESMD
Enhancer of split mdelta protein

1

0

High-throughput

0.518

High

1176445

FOXO
Forkhead box protein O

1

0

High-throughput

0.518

High

1176449

Q9VAY8
Buddy of Hmr 1

1

0

High-throughput

0.518

High

1176446

DOM
Helicase domino

1

6

Small-scale

0.515

High

1176450

Q9VB52
LD05287p

1

14

Small-scale

0.515

High

1176457

CDK8
Cyclin-dependent kinase 8

1

14

Small-scale

0.515

High

575845

CCNA
G2/mitotic-specific cyclin-A

1

11

Small-scale

0.501

High

660388

CDK1
Cyclin-dependent kinase 1

1

14

Small-scale

0.501

High

304848

E2F2
Transcription factor E2F2

1

14

High-throughput

0.492

High

1176443

Q8T052
TATA box-binding protein-like 1

1

1

Small-scale

0.481

High

1176448

Q9V9Q2
IP01335p

1

1

High-throughput

0.481

High

1176451

Q9VD04
Uncharacterized protein, isoform B

1

6

High-throughput

0.481

High

1176456

Q9VRQ6
Uncharacterized protein, isoform A

1

1

High-throughput

0.481

High

195737

ORC1
Origin recognition complex subunit 1

1

5

Small-scale

0.479

High

717024

SCAL
Protein scalloped

1

2

Small-scale

0.479

High

1064528

GAGA
Transcription activator GAGA

1

4

Small-scale

0.479

High

1176444

Q94883
DNA replication-related element factor, isoform A

1

0

Small-scale

0.460

High

1172732

ORC2
Origin recognition complex subunit 2

1

0

Small-scale

0.458

High

121068

M9PEQ7
Uncharacterized protein, isoform B

1

1

High-throughput

0.457

High

1176442

Q8SXJ5
RE19601p

1

1

High-throughput

0.457

High

1176452

Q9VD05
RT01151p

1

6

High-throughput

0.457

High

1176455

Q9VLS7
LD21067p

1

1

High-throughput

0.445

High

1176454

MOCS3
Adenylyltransferase and sulfurtransferase MOCS3

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025