HitPredict

Interactor 1: MARCS (P29966)
Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Gene: MARCKS

Interactor 2: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	32707033, 7588787
Identification Methods	affinity chromatography technology, enzymatic study, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 332 Hs			1 592
+	Hs
		669910 MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00		KPCI_HUMAN (1-592): 0: 654: 69.87
+	Hs
		554297 MUC1_HUMAN (68-331): 2.42e-11: 66.7: 10.57		KPCD_HUMAN (85-585): 1.92e-177: 519: 36.26
+	Hs
		670287 MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00		AKT3_HUMAN (171-582): 2.36e-153: 450: 37.24
+	Hs
		117011 Q6NVI1_HUMAN (1-151): 5.47e-14: 70.7: 100.00		SGK1_HUMAN (199-583): 7.41e-144: 424: 38.36
+	Hs
		408560 MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00		KPCB_HUMAN (85-187): 1.04e-21: 101: 27.18