HitPredict

Interactor 1: PRDX3 (P30048)
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) (Thioredoxin-dependent peroxiredoxin 3)
Gene: PRDX3

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20562859
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 256 Hs			1 125
+	Hs
		671018 PRDX3_HUMAN (1-256): 3.48e-122: 349: 100.00		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		670919 PRDX3_HUMAN (1-256): 3.48e-122: 349: 100.00		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		305981 PRDX3_HUMAN (1-256): 3.48e-122: 349: 100.00		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		671016 PRDX3_HUMAN (1-256): 3.48e-122: 349: 100.00		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		685765 PRDX2_HUMAN (58-255): 2.07e-104: 302: 63.13		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		1026773 PRDX4_HUMAN (35-255): 3.38e-103: 302: 58.82		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		685770 PRDX2_HUMAN (58-255): 2.07e-104: 302: 63.13		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		685655 PRDX2_HUMAN (58-255): 2.07e-104: 302: 63.13		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		891123 PRDX4_HUMAN (35-255): 3.38e-103: 302: 58.82		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		989387 PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		305989 PRDX2_HUMAN (58-255): 2.07e-104: 302: 63.13		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		306152 PRDX4_HUMAN (35-255): 3.38e-103: 302: 58.82		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1026768 PRDX4_HUMAN (35-255): 3.38e-103: 302: 58.82		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		685768 PRDX2_HUMAN (58-255): 2.07e-104: 302: 63.13		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		989392 PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		891102 PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306127 PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		989390 PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		670683 PRDX6_HUMAN (63-254): 3.4e-68: 211: 25.25		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		670762 PRDX6_HUMAN (63-254): 3.4e-68: 211: 25.25		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46