HitPredict

Interactor 1: DNJB1 (P25685)
DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1)
Gene: DNAJB1

Interactor 2: TMTC3 (Q6ZXV5)
Protein O-mannosyl-transferase TMTC3 (EC 2.4.1.109) (Protein SMILE) (Transmembrane O-mannosyltransferase targeting cadherins 3) (Transmembrane and tetratricopeptide repeat-containing 3)
Gene: TMTC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 Hs			1 915
+	Hs
		1257558 DJB11_HUMAN (2-338): 1.47e-104: 312: 32.26		TMTC3_HUMAN (1-915): 0: 847: 100.00
+	Hs
		679242 DNJB1_HUMAN (1-340): 6.44e-141: 404: 100.00		DNJC7_HUMAN (388-650): 6.16e-18: 89.9: 12.14
+	Hs
		1405896 DNJB4_HUMAN (1-339): 4.5e-138: 397: 64.60		DNJC7_HUMAN (388-650): 6.16e-18: 89.9: 12.14
+	Hs
		679077 DNJB1_HUMAN (1-340): 6.44e-141: 404: 100.00		STIP1_HUMAN (389-542): 8.68e-12: 70.6: 9.74
+	Hs
		298903 DNJB5_HUMAN (1-339): 5.08e-130: 377: 59.71		DNJC3_HUMAN (617-882): 1.56e-19: 95.2: 10.71
+	Hs
		731670 DNJB4_HUMAN (1-339): 4.5e-138: 397: 64.60		STIP1_HUMAN (389-542): 8.68e-12: 70.6: 9.74
+	Hs
		298951 DNJB5_HUMAN (1-339): 5.08e-130: 377: 59.71		DNJC7_HUMAN (388-650): 6.16e-18: 89.9: 12.14
+	Hs
		185461 DNJA1_HUMAN (5-339): 8.06e-118: 347: 32.77		OGT1_HUMAN (366-535): 2.35e-21: 102: 11.18
+	Hs
		298889 DNJB5_HUMAN (1-339): 5.08e-130: 377: 59.71		STIP1_HUMAN (389-542): 8.68e-12: 70.6: 9.74
+	Hs
		185285 DNJA2_HUMAN (2-339): 7.03e-116: 343: 33.24		OGT1_HUMAN (366-535): 2.35e-21: 102: 11.18
+	Hs
		258859 DNJA2_HUMAN (2-339): 7.03e-116: 343: 33.24		DNJC3_HUMAN (617-882): 1.56e-19: 95.2: 10.71
+	Hs
		727938 DNJA1_HUMAN (5-339): 8.06e-118: 347: 32.77		DNJC7_HUMAN (388-650): 6.16e-18: 89.9: 12.14
+	Hs
		1098452 DNJA4_HUMAN (5-339): 1.29e-115: 341: 32.49		DNJC3_HUMAN (617-882): 1.56e-19: 95.2: 10.71
+	Hs
		259065 DNJA2_HUMAN (2-339): 7.03e-116: 343: 33.24		DNJC7_HUMAN (388-650): 6.16e-18: 89.9: 12.14
+	Hs
		1358953 DNJA4_HUMAN (5-339): 1.29e-115: 341: 32.49		DNJC7_HUMAN (388-650): 6.16e-18: 89.9: 12.14
+	Hs
		727692 DNJA1_HUMAN (5-339): 8.06e-118: 347: 32.77		STIP1_HUMAN (389-542): 8.68e-12: 70.6: 9.74
+	Hs
		258778 DNJA2_HUMAN (2-339): 7.03e-116: 343: 33.24		STIP1_HUMAN (389-542): 8.68e-12: 70.6: 9.74
+	Hs
		1098495 DJB11_HUMAN (2-338): 1.47e-104: 312: 32.26		DNJC3_HUMAN (617-882): 1.56e-19: 95.2: 10.71
+	Sc
		577530 MAS5_YEAST (5-339): 1e-109: 327: 31.56		CYC8_YEAST (732-833): 6.85e-09: 61.8: 10.78
+	Sc
		577529 SIS1_YEAST (6-336): 1.71e-47: 165: 34.63		CYC8_YEAST (732-833): 6.85e-09: 61.8: 10.78