HitPredict

Interactor 1: PDIA3 (P30101)
Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60)
Gene: PDIA3

Interactor 2: TAP1 (Q03518)
Antigen peptide transporter 1 (APT1) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 2) (Peptide supply factor 1) (Peptide transporter PSF1) (PSF-1) (Peptide transporter TAP1) (Peptide transporter involved in antigen processing 1) (Really interesting new gene 4 protein) (RING4)
Gene: TAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	11823531, 30833792, 9545232, 17055437
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002250 - adaptive immune response GO:0005783 - endoplasmic reticulum GO:0042824 - MHC class I peptide loading complex
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 748
+	Hs
		423209 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		TAP1_HUMAN (1-748): 0: 624: 100.00
+	Hs
		976714 PDIA2_HUMAN (356-501): 1e-23: 106: 22.30		TAP1_HUMAN (1-748): 0: 624: 100.00