Interactor 1: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27

Interactor 2: CDC16 (Q13042)
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
Gene: CDC16

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.990

The method score is based on:

Property Details
Experiments 12956947, 25306918, 27114510, 32152539, 32076268, 9628895, 10922056, 35271311, 35952650, 14657031, 9356466, 22193957, 17187060, 16364912, 21043528, 16648845, 26496610, 24100295, 28514442, 27173435 and 5 others

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Identification Methods affinity chromatography technology, biochemical, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC3~ANAPC3, ANAPC3~TPR_12, TPR_1~TPR_12, ANAPC3~TPR_8, TPR_12~TPR_8
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
and 7 others

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Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 824
Hs

1 620
+ Xl
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Xl
+ Xl
+ Xl
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ At
+ Sp

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Last updated: 15 Jul 2024