Protein: S38A1
Sodium-coupled neutral amino acid symporter 1 (Amino acid transporter A1) (N-system amino acid transporter 2) (Solute carrier family 38 member 1) (System A amino acid transporter 1) (System N amino acid transporter 1)

Gene: S38A1, SLC38A1
Organism: Homo sapiens
Interactions: 182
UniProt ID: Q9H2H9

Gene Ontology (top 5):
GO:0001504 - neurotransmitter uptake
GO:0003333 - amino acid transmembrane transport
GO:0005283 - amino acid:sodium symporter activity
GO:0005295 - neutral L-amino acid:sodium symporter activity
GO:0005298 - proline:sodium symporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1431910

SCN3B
Sodium channel regulatory subunit beta-3

2

3

High-throughput

0.783

High

375939

RASK
GTPase KRas

3

12

High-throughput

0.640

High

181431

PGRC2
Membrane-associated progesterone receptor component 2

2

2

High-throughput

0.606

High

194749

FFAR2
Free fatty acid receptor 2

2

7

High-throughput

0.606

High

1031680

ILRL1
Interleukin-1 receptor-like 1

2

1

High-throughput

0.606

High

1126174

GRM2
Metabotropic glutamate receptor 2

2

1

High-throughput

0.606

High

1134164

NTCP
Hepatic sodium/bile acid cotransporter

2

3

High-throughput

0.606

High

1186044

SOAT
Sodium-dependent organic anion transporter

2

3

High-throughput

0.606

High

1292548

AMGO1
Amphoterin-induced protein 1

2

2

High-throughput

0.606

High

1351703

GP152
Probable G-protein coupled receptor 152

2

3

High-throughput

0.606

High

1359318

SSMM1
Serine-rich single-pass membrane protein 1

2

2

High-throughput

0.606

High

1410016

PD1L2
Programmed cell death 1 ligand 2

2

4

High-throughput

0.606

High

218760

TGON2
Trans-Golgi network integral membrane protein 2

2

3

High-throughput

0.584

High

374189

RASN
GTPase NRas

2

12

High-throughput

0.584

High

540670

LAMP1
Lysosome-associated membrane glycoprotein 1

2

7

High-throughput

0.584

High

630967

RAB4A
Ras-related protein Rab-4A

2

6

High-throughput

0.584

High

975235

ARF6
ADP-ribosylation factor 6

2

3

High-throughput

0.584

High

976555

RB11A
Ras-related protein Rab-11A

2

4

High-throughput

0.584

High

978295

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

549886

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.580

High

666022

IBP5
Insulin-like growth factor-binding protein 5

2

0

High-throughput

0.580

High

1030383

PMP22
Peripheral myelin protein 22

2

0

High-throughput

0.580

High

1254311

TMPPE
Transmembrane protein with metallophosphoesterase domain

2

0

High-throughput

0.580

High

1420031

SMIM3
Small integral membrane protein 3

2

0

High-throughput

0.580

High

1431897

TMM60
Transmembrane protein 60

2

0

High-throughput

0.580

High

1431907

RPRM
Protein reprimo

2

0

High-throughput

0.580

High

1431916

S13A4
Solute carrier family 13 member 4

2

0

High-throughput

0.580

High

617596

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

2

2

High-throughput

0.574

High

1109047

AQP6
Aquaporin-6

2

6

High-throughput

0.553

High

1329665

SERP2
Stress-associated endoplasmic reticulum protein 2

2

1

High-throughput

0.553

High

321352

ERLN2
Erlin-2

1

1

High-throughput

0.536

High

328740

VAMP5
Vesicle-associated membrane protein 5

1

1

High-throughput

0.536

High

341475

CDS2
Phosphatidate cytidylyltransferase 2

1

1

High-throughput

0.536

High

507365

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

5

High-throughput

0.536

High

508610

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

High-throughput

0.536

High

521004

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

2

High-throughput

0.536

High

627410

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

3

High-throughput

0.536

High

665709

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

2

High-throughput

0.536

High

689858

CD27
CD27 antigen

1

3

High-throughput

0.536

High

699114

CALX
Calnexin

1

2

High-throughput

0.536

High

852850

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

1

High-throughput

0.536

High

869979

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

3

High-throughput

0.536

High

1031861

LAT1
Large neutral amino acids transporter small subunit 1

1

5

High-throughput

0.536

High

1139568

S39AE
Metal cation symporter ZIP14

1

1

High-throughput

0.536

High

1259494

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.536

High

1312252

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.536

High

1406232

CHP1
Calcineurin B homologous protein 1

1

6

High-throughput

0.536

High

1431920

VDAC3
Non-selective voltage-gated ion channel VDAC3

1

1

High-throughput

0.536

High

63699

A5PKU2
TUSC5 protein

1

7

High-throughput

0.515

High

193449

GPR42
G-protein coupled receptor 42

1

8

High-throughput

0.515

High

329003

RTN3
Reticulon-3

1

0

High-throughput

0.513

High

338654

AGRL2
Adhesion G protein-coupled receptor L2

1

0

High-throughput

0.513

High

360474

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.513

High

784717

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

0

High-throughput

0.513

High

963131

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

0

High-throughput

0.513

High

1147844

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.513

High

1242315

SFXN4
Sideroflexin-4

1

0

High-throughput

0.513

High

1362083

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

0

High-throughput

0.513

High

1412284

NTPCR
Cancer-related nucleoside-triphosphatase

1

0

High-throughput

0.513

High

1431922

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

0

High-throughput

0.513

High

390759

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.493

High

220990

XPOT
Exportin-T

1

1

High-throughput

0.489

High

298801

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

2

High-throughput

0.489

High

299692

ATP5L
ATP synthase F(0) complex subunit g, mitochondrial

1

1

High-throughput

0.489

High

940627

ATP5E
ATP synthase F(1) complex subunit epsilon, mitochondrial

1

5

High-throughput

0.489

High

940688

ATP5I
ATP synthase F(0) complex subunit e, mitochondrial

1

2

High-throughput

0.489

High

1199265

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

3

High-throughput

0.489

High

1205034

RABL3
Rab-like protein 3

1

6

High-throughput

0.489

High

1364091

SNX19
Sorting nexin-19

1

1

High-throughput

0.489

High

1382721

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

1

High-throughput

0.489

High

1431899

SG196
Protein O-mannose kinase

1

2

High-throughput

0.489

High

1431909

TBA8
Tubulin alpha-8 chain

1

1

High-throughput

0.489

High

230430

CREB3
Cyclic AMP-responsive element-binding protein 3

1

1

High-throughput

0.481

High

1312127

TARG1
Trafficking regulator of GLUT4 1

1

7

High-throughput

0.481

High

125608

LEG9
Galectin-9

1

6

High-throughput

0.479

High

126795

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

189833

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

226198

STX6
Syntaxin-6

1

3

High-throughput

0.479

High

299369

FLOT1
Flotillin-1

1

2

High-throughput

0.479

High

327443

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.479

High

341140

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.479

High

374923

RASH
GTPase HRas

1

8

High-throughput

0.479

High

404409

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

412594

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

463762

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.479

High

466453

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

562388

LAMP2
Lysosome-associated membrane glycoprotein 2

1

7

High-throughput

0.479

High

581280

RAC2
Ras-related C3 botulinum toxin substrate 2

1

19

High-throughput

0.479

High

601439

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

604199

CXA1
Gap junction alpha-1 protein

1

7

High-throughput

0.479

High

630628

RAB3B
Ras-related protein Rab-3B

1

3

High-throughput

0.479

High

631467

RAB5A
Ras-related protein Rab-5A

1

6

High-throughput

0.479

High

643064

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

1

High-throughput

0.479

High

648664

FGFR4
Fibroblast growth factor receptor 4

1

3

High-throughput

0.479

High

710485

EPHA2
Ephrin type-A receptor 2

1

3

High-throughput

0.479

High

715764

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.479

High

880683

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.479

High

901033

RAB5C
Ras-related protein Rab-5C

1

6

High-throughput

0.479

High

902063

RAB9A
Ras-related protein Rab-9A

1

6

High-throughput

0.479

High

910193

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

931893

EPHA5
Ephrin type-A receptor 5

1

3

High-throughput

0.479

High

936447

AFAD
Afadin

1

2

High-throughput

0.479

High

941838

ARL4C
ADP-ribosylation factor-like protein 4C

1

8

High-throughput

0.479

High

945095

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.479

High

953665

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

955578

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

956486

RAB2A
Ras-related protein Rab-2A

1

6

High-throughput

0.479

High

962467

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

962825

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

988696

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

989114

AP2B1
AP-2 complex subunit beta

1

1

High-throughput

0.479

High

1014961

ARF1
ADP-ribosylation factor 1

1

3

High-throughput

0.479

High

1015117

ARF5
ADP-ribosylation factor 5

1

3

High-throughput

0.479

High

1015773

RHOG
Rho-related GTP-binding protein RhoG

1

19

High-throughput

0.479

High

1041279

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

1087278

STX4
Syntaxin-4

1

4

High-throughput

0.479

High

1145104

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.479

High

1151869

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

1159836

OCLN
Occludin

1

1

High-throughput

0.479

High

1163417

CAH9
Carbonic anhydrase 9

1

2

High-throughput

0.479

High

1233475

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.479

High

1235328

STYK1
Tyrosine-protein kinase STYK1

1

3

High-throughput

0.479

High

1270990

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1322980

CXD3
Gap junction delta-3 protein

1

7

High-throughput

0.479

High

1326511

ARL14
ADP-ribosylation factor-like protein 14

1

5

High-throughput

0.479

High

1366879

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

1381512

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

3

High-throughput

0.479

High

1381960

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.479

High

1396624

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.479

High

1431898

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1431902

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1431906

TMPS4
Transmembrane protease serine 4

1

3

High-throughput

0.479

High

1431908

ARL15
ADP-ribosylation factor-like protein 15

1

6

High-throughput

0.479

High

1431911

ELOV5
Very long chain fatty acid elongase 5

1

4

High-throughput

0.479

High

1431913

TM216
Transmembrane protein 216

1

1

High-throughput

0.479

High

1431914

ANFY1
Rabankyrin-5

1

1

High-throughput

0.479

High

1431915

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

1431918

ALK
ALK tyrosine kinase receptor

1

4

High-throughput

0.479

High

1431919

LAMP3
Lysosome-associated membrane glycoprotein 3

1

7

High-throughput

0.479

High

181735

CTDSL
CTD small phosphatase-like protein

1

0

High-throughput

0.458

High

346316

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

556337

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

939969

TPTE
Putative tyrosine-protein phosphatase TPTE

1

0

High-throughput

0.458

High

1276312

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

182768

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.445

High

380141

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

2

High-throughput

0.445

High

867678

GPR12
G-protein coupled receptor 12

1

3

High-throughput

0.445

High

1273802

NIPA1
Magnesium transporter NIPA1

1

1

High-throughput

0.445

High

1291892

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

4

High-throughput

0.445

High

1308969

S22A9
Organic anion transporter 7

1

1

High-throughput

0.445

High

1431917

YLAT1
Y+L amino acid transporter 1

1

5

High-throughput

0.445

High

139981

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

414599

P53
Cellular tumor antigen p53

1

1

High-throughput

0.437

High

519223

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

1

High-throughput

0.437

High

827258

ARL1
ADP-ribosylation factor-like protein 1

1

5

High-throughput

0.437

High

1146475

KS6A2
Ribosomal protein S6 kinase alpha-2

1

1

High-throughput

0.437

High

1197706

MIDN
Midnolin

1

1

High-throughput

0.437

High

1255500

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1293145

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

1086102

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.426

High

1236311

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1431904

ANKH
Mineralization regulator ANKH

1

0

High-throughput

0.426

High

1211960

S35F1
Solute carrier family 35 member F1

1

3

High-throughput

0.407

High

1217952

AT5EL
ATP synthase subunit epsilon-like protein, mitochondrial

1

5

High-throughput

0.407

High

1431900

TBA4B
Tubulin-like protein alpha-4B

1

2

High-throughput

0.407

High

1379880

FATE1
Fetal and adult testis-expressed transcript protein

3

0

High-throughput

0.352

High

335576

BMP10
Bone morphogenetic protein 10

2

0

High-throughput

0.316

High

351726

SG1D1
Secretoglobin family 1D member 1

2

0

High-throughput

0.316

High

1295797

C1QL4
Complement C1q-like protein 4

2

0

High-throughput

0.316

High

1053743

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

0

High-throughput

0.282

High

367192

ATP6
ATP synthase F(0) complex subunit a

1

0

High-throughput

0.279

Low

716735

ATPD
ATP synthase F(1) complex subunit delta, mitochondrial

1

0

High-throughput

0.279

Low

1359192

MAIP1
m-AAA protease-interacting protein 1, mitochondrial

1

0

High-throughput

0.279

Low

1394480

ATPMK
ATP synthase F(0) complex subunit k, mitochondrial

1

0

High-throughput

0.279

Low

1431901

GHC1
Mitochondrial glutamate carrier 1

1

0

High-throughput

0.279

Low

1431903

TM165
Putative divalent cation/proton antiporter TMEM165

1

0

High-throughput

0.279

Low

1431905

OSTC
Oligosaccharyltransferase complex subunit OSTC

1

0

High-throughput

0.279

Low

1431912

HACD3
Very-long-chain

1

0

High-throughput

0.279

Low

1431921

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.279

Low

516280

DWORF
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

1

0

High-throughput

0.268

Low

122645

UBXN8
UBX domain-containing protein 8

1

0

High-throughput

0.249

Low

294316

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025