HitPredict

Interactor 1: COR1A (P31146)
Coronin-1A (Coronin-like protein A) (Clipin-A) (Coronin-like protein p57) (Tryptophan aspartate-containing coat protein) (TACO)
Gene: CORO1A

Interactor 2: POC1B (Q8TC44)
POC1 centriolar protein homolog B (Pix1) (Proteome of centriole protein 1B) (WD repeat-containing protein 51B)
Gene: POC1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DUF1899~WD40, WD40~WD40, WD40~WD40_4
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 461 Hs			1 478
+	Hs
		678289 COR1A_HUMAN (1-461): 2.23e-128: 381: 100.00		POC1A_HUMAN (89-468): 1.31e-101: 311: 29.41
+	Hs
		1163297 CORO6_HUMAN (1-458): 1.61e-123: 369: 67.10		POC1A_HUMAN (89-468): 1.31e-101: 311: 29.41
+	Hs
		1240442 POC1B_HUMAN (163-390): 6.16e-44: 162: 14.04		POC1A_HUMAN (89-468): 1.31e-101: 311: 29.41
+	Dm
		186198 Q7JVY0_DROME (1-461): 5.44e-92: 290: 48.47		GBLP_DROME (12-218): 4.32e-15: 77.8: 27.40
+	Dm
		1358845 WDS_DROME (2-254): 7.37e-57: 193: 17.19		WDS_DROME (312-443): 4.23e-23: 102: 8.21
+	Sc
		630844 NLE1_YEAST (100-402): 2.64e-52: 185: 12.61		NLE1_YEAST (312-444): 2.66e-19: 92.5: 12.68
+	Hs
		197071 SNR40_HUMAN (2-158): 5.82e-29: 118: 16.15		PRP4_HUMAN (214-438): 4.93e-33: 133: 16.17
+	Hs
		903418 WDR5_HUMAN (3-110): 7.1e-17: 83.4: 16.96		FBXW7_HUMAN (213-440): 6.09e-42: 160: 17.47
+	Hs
		903428 SNR40_HUMAN (2-158): 5.82e-29: 118: 16.15		WDR5_HUMAN (300-443): 5.44e-25: 107: 7.53
+	Hs
		196984 WDR5_HUMAN (3-110): 7.1e-17: 83.4: 16.96		PRP4_HUMAN (214-438): 4.93e-33: 133: 16.17
+	Hs
		903551 NLE1_HUMAN (2-109): 1.41e-22: 101: 18.52		WDR5_HUMAN (300-443): 5.44e-25: 107: 7.53
+	Hs
		921751 NLE1_HUMAN (2-109): 1.41e-22: 101: 18.52		GBB2_HUMAN (180-358): 2.7e-19: 90.8: 16.39
+	Hs
		903077 WDR5_HUMAN (3-110): 7.1e-17: 83.4: 16.96		WDR5_HUMAN (300-443): 5.44e-25: 107: 7.53
+	At
		1164331 TAF5_ARATH (30-194): 9.2e-29: 121: 17.32		TAF5_ARATH (12-131): 1.56e-11: 68.6: 28.33
+	Hs
		903349 WDR5_HUMAN (3-110): 7.1e-17: 83.4: 16.96		WDR5B_HUMAN (299-443): 8.32e-24: 103: 6.12
+	Hs
		792949 WDR5_HUMAN (3-110): 7.1e-17: 83.4: 16.96		LIS1_HUMAN (313-443): 2.88e-21: 97.5: 9.77
+	Hs
		1074799 PHIP_HUMAN (2-159): 1.54e-21: 100: 13.30		TAF5_HUMAN (155-300): 3.58e-10: 64.3: 30.41
+	Hs
		1346954 NLE1_HUMAN (2-109): 1.41e-22: 101: 18.52		NLE1_HUMAN (358-439): 1.89e-09: 61.7: 8.33