Protein: IASPP
RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein)

Gene: IASPP, PPP1R13L
Organism: Homo sapiens
Interactions: 96
UniProt ID: Q8WUF5

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003215 - cardiac right ventricle morphogenesis
GO:0003229 - ventricular cardiac muscle tissue development
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

414291

P53
Cellular tumor antigen p53

10

15

Small-scale

0.971

High

626300

NFKB1
Nuclear factor NF-kappa-B p105 subunit

3

20

Small-scale

0.839

High

1045568

TF65
Transcription factor p65

2

12

Small-scale

0.821

High

1121476

KEAP1
Kelch-like ECH-associated protein 1

2

4

Small-scale

0.806

High

1356636

IASPP
RelA-associated inhibitor

2

16

Small-scale

0.792

High

1026749

NFKB2
Nuclear factor NF-kappa-B p100 subunit

2

20

Small-scale

0.789

High

967876

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

11

20

Small-scale

0.760

High

981607

RAN
GTP-binding nuclear protein Ran

1

12

Small-scale

0.757

High

968389

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

8

20

Small-scale

0.753

High

1152169

MARE1
Microtubule-associated protein RP/EB family member 1

8

4

Small-scale

0.751

High

786744

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

6

20

Small-scale

0.732

High

1356642

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

20

High-throughput

0.698

High

1356647

TANC2
Protein TANC2

2

15

High-throughput

0.694

High

239326

MYPT2
Protein phosphatase 1 regulatory subunit 12B

1

19

High-throughput

0.691

High

407668

S100B
Protein S100-B

1

2

High-throughput

0.691

High

840974

ABL2
Tyrosine-protein kinase ABL2

1

16

High-throughput

0.691

High

848341

MAGA4
Melanoma-associated antigen 4

3

11

High-throughput

0.667

High

186775

P73
Tumor protein p73

1

15

Small-scale

0.647

High

1006584

SRPK2
SRSF protein kinase 2

1

3

High-throughput

0.647

High

1356645

P63
Tumor protein 63

1

15

Small-scale

0.647

High

1227143

A16L1
Autophagy-related protein 16-1

3

17

Small-scale

0.633

High

1148864

PP1R7
Protein phosphatase 1 regulatory subunit 7

2

9

High-throughput

0.628

High

1323915

KLH34
Kelch-like protein 34

1

6

High-throughput

0.618

High

331184

KI20A
Kinesin-like protein KIF20A

1

16

High-throughput

0.618

High

891262

GSK3A
Glycogen synthase kinase-3 alpha

1

13

High-throughput

0.618

High

891697

GSK3B
Glycogen synthase kinase-3 beta

1

14

High-throughput

0.618

High

1113825

CUL3
Cullin-3

1

17

High-throughput

0.618

High

1140608

KIF14
Kinesin-like protein KIF14

1

11

High-throughput

0.618

High

1356640

AURKB
Aurora kinase B

1

4

High-throughput

0.618

High

1067535

EP300
Histone acetyltransferase p300

2

16

Small-scale

0.611

High

1356641

WDR83
WD repeat domain-containing protein 83

3

8

High-throughput

0.609

High

167521

TX1B3
Tax1-binding protein 3

2

12

High-throughput

0.601

High

537591

HSP7C
Heat shock cognate 71 kDa protein

2

11

High-throughput

0.601

High

1279011

TAFA3
Chemokine-like protein TAFA-3

2

1

High-throughput

0.574

High

465008

SP1
Transcription factor Sp1

1

10

Small-scale

0.561

High

822782

VHL
von Hippel-Lindau disease tumor suppressor

1

1

Small-scale

0.561

High

1356656

AMFR
E3 ubiquitin-protein ligase AMFR

1

1

Small-scale

0.561

High

175138

SC16A
Protein transport protein Sec16A

1

7

High-throughput

0.536

High

223209

PRC1
Protein regulator of cytokinesis 1

1

6

High-throughput

0.536

High

261532

B4GT2
Beta-1,4-galactosyltransferase 2

1

1

High-throughput

0.536

High

338919

CBX6
Chromobox protein homolog 6

1

15

High-throughput

0.536

High

347206

BAG2
BAG family molecular chaperone regulator 2

1

7

High-throughput

0.536

High

430163

JUN
Transcription factor Jun

1

10

High-throughput

0.536

High

564120

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.536

High

848689

MAGA9
Melanoma-associated antigen 9

1

11

High-throughput

0.536

High

916107

NKX25
Homeobox protein Nkx-2.5

1

12

High-throughput

0.536

High

1023842

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

2

High-throughput

0.536

High

1306944

I2BP1
Interferon regulatory factor 2-binding protein 1

1

1

High-throughput

0.536

High

1356650

GTSE1
G2 and S phase-expressed protein 1

1

1

High-throughput

0.536

High

1356655

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

2

High-throughput

0.536

High

1163658

PPR3A
Protein phosphatase 1 regulatory subunit 3A

2

2

Small-scale

0.533

High

1136662

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.517

High

65787

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

0

High-throughput

0.513

High

914058

SPSY
Spermine synthase

1

0

High-throughput

0.513

High

943101

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

1207244

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

1356649

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

1356660

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

1161333

HIF1A
Hypoxia-inducible factor 1-alpha

1

7

Small-scale

0.501

High

292702

RENR
Renin receptor

1

1

High-throughput

0.489

High

733403

CCR1
C-C chemokine receptor type 1

1

3

High-throughput

0.489

High

1206501

PRC2B
Protein PRRC2B

1

20

High-throughput

0.489

High

1325808

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

4

High-throughput

0.489

High

1356651

HPBP1
Hsp70-binding protein 1

1

2

High-throughput

0.489

High

1356652

NHSL3
NHS-like protein 3

1

14

High-throughput

0.489

High

1356653

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

2

High-throughput

0.489

High

1356659

CLC11
C-type lectin domain family 11 member A

1

1

High-throughput

0.489

High

173132

XPO1
Exportin-1

1

13

High-throughput

0.479

High

556244

CADH1
Cadherin-1

1

5

High-throughput

0.479

High

714292

PML
Protein PML

1

10

High-throughput

0.479

High

848286

MAGA3
Melanoma-associated antigen 3

1

11

Small-scale

0.479

High

872573

SOX2
Transcription factor SOX-2

1

9

High-throughput

0.479

High

1107966

SQSTM
Sequestosome-1

1

12

High-throughput

0.479

High

1156685

NF2L2
Nuclear factor erythroid 2-related factor 2

1

6

Small-scale

0.479

High

1156793

E2F4
Transcription factor E2F4

1

2

High-throughput

0.479

High

1198470

CEP55
Centrosomal protein of 55 kDa

1

3

Small-scale

0.479

High

1294161

CEP57
Centrosomal protein of 57 kDa

1

1

High-throughput

0.479

High

1356637

ESR2
Estrogen receptor beta

1

19

High-throughput

0.479

High

1356638

HDAC2
Histone deacetylase 2

1

9

High-throughput

0.479

High

1356639

CBP
CREB-binding protein

1

14

Small-scale

0.479

High

1356643

EGLN1
Egl nine homolog 1

1

6

Small-scale

0.479

High

1356644

ATG5
Autophagy protein 5

1

2

Small-scale

0.479

High

1356648

ANLN
Anillin

1

3

High-throughput

0.479

High

1356654

ZRAN1
Ubiquitin thioesterase ZRANB1

1

12

High-throughput

0.479

High

1339626

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

890372

NU153
Nuclear pore complex protein Nup153

1

18

Small-scale

0.445

High

964688

DCAF7
DDB1- and CUL4-associated factor 7

1

5

High-throughput

0.445

High

965569

NTF2
Nuclear transport factor 2

1

2

Small-scale

0.445

High

1356646

PKHA4
Pleckstrin homology domain-containing family A member 4

1

19

High-throughput

0.437

High

1356658

MARE3
Microtubule-associated protein RP/EB family member 3

1

4

Small-scale

0.437

High

598755

ANFB
Natriuretic peptides B

1

0

High-throughput

0.279

Low

1356661

PCDGE
Protocadherin gamma-B2

1

0

High-throughput

0.279

Low

1356657

TMCO1
Calcium load-activated calcium channel

1

0

Small-scale

0.249

Low

1308840

P3H3
Prolyl 3-hydroxylase 3

1

0

High-throughput

0.232

Low

1311007

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025