HitPredict - High confidence protein-protein interactions

Interactor 1: KAP1 (P31321)
cAMP-dependent protein kinase type I-beta regulatory subunit
Gene: PRKAR1B

Interactor 2: KAP1 (P31321)
cAMP-dependent protein kinase type I-beta regulatory subunit
Gene: PRKAR1B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	12634056
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	cNMP_binding~cNMP_binding, RIIa~RIIa
Common GO terms	GO:0004862 - cAMP-dependent protein kinase inhibitor activity GO:0005771 - multivesicular body GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005952 - cAMP-dependent protein kinase complex and 15 others more... GO:0006468 - protein phosphorylation GO:0007611 - learning or memory GO:0008603 - cAMP-dependent protein kinase regulator activity GO:0030552 - cAMP binding GO:0034236 - protein kinase A catalytic subunit binding GO:0097546 - ciliary base GO:0098685 - Schaffer collateral - CA1 synapse GO:0098686 - hippocampal mossy fiber to CA3 synapse GO:0098693 - regulation of synaptic vesicle cycle GO:0098794 - postsynapse GO:0098978 - glutamatergic synapse GO:1900273 - positive regulation of long-term synaptic potentiation GO:1903367 - positive regulation of fear response GO:2000463 - positive regulation of excitatory postsynaptic potential GO:2000480 - negative regulation of cAMP-dependent protein kinase activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1	381
Hs

1	381

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Last updated: 15 Jul 2024