HitPredict

Interactor 1: DNJA1 (P31689)
DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)
Gene: DNAJA1

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 397 Hs			1 839
+	Hs
		243425 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		1081563 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		384352 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		507875 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		243251 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		243277 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		243293 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		385330 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		609471 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73
+	Hs
		508145 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		608081 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		243261 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		681409 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		411313 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		435551 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		243254 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		243262 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		243669 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		ALK_HUMAN (513-816): 2.78e-59: 222: 39.03
+	Hs
		411469 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		435729 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16