HitPredict

Interactor 1: DNJA1 (P31689)
DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)
Gene: DNAJA1

Interactor 2: KS6B2 (Q9UBS0)
Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta)
Gene: RPS6KB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25324306
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 397 Hs			1 482
+	Hs
		243655 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		KS6B2_HUMAN (1-482): 0: 531: 100.00
+	Hs
		681410 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		KPCE_HUMAN (2-395): 2.02e-145: 435: 34.23
+	Hs
		568560 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		KAPCA_HUMAN (31-387): 1.3e-144: 419: 34.17
+	Hs
		636433 DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59		KS6B2_HUMAN (1-482): 0: 531: 100.00
+	Dm
		1276807 Q9VFV9_DROME (1-397): 1.49e-137: 400: 58.77		Q94533_DROME (43-480): 1.84e-161: 467: 63.24
+	Dm
		1213393 Q9VFV9_DROME (1-397): 1.49e-137: 400: 58.77		AKT1_DROME (19-395): 5.26e-150: 442: 39.37
+	Hs
		636252 DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59		AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19
+	Sc
		520583 MAS5_YEAST (1-396): 8.35e-140: 406: 45.37		YPK1_YEAST (54-397): 2.05e-97: 309: 46.40
+	Dm
		1365713 Q9VFV9_DROME (1-397): 1.49e-137: 400: 58.77		Q9VR61_DROME (18-403): 5.76e-91: 297: 24.44