Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Interactor 2: SHAN2 (Q9UPX8)
SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (Proline-rich synapse-associated protein 1)
Gene: SHANK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 34941261
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Pkinase, Pkinase~SAM_1
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0098978 - glutamatergic synapse
GO:0099175 - regulation of postsynapse organization
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 480
Hs

1 1849
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+ Rn
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024