HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: KIF23 (Q02241)
Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1)
Gene: KIF23

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.752

Property	Details
Experiments	26496610, 31586073, 17353931, 33961781, 35271311, 36931259, 15324660, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 960
+	Hs
		909459 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		KIF23_HUMAN (1-960): 0: 670: 100.00
+	Hs
		926943 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		KIF23_HUMAN (1-960): 0: 670: 100.00
+	Hs
		231490 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		KIF1B_HUMAN (22-927): 1.18e-124: 418: 16.49
+	Hs
		231459 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		KIF1B_HUMAN (22-927): 1.18e-124: 418: 16.49
+	Hs
		910062 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		KI13B_HUMAN (23-845): 2.95e-123: 414: 16.08
+	Hs
		683742 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		KI13B_HUMAN (23-845): 2.95e-123: 414: 16.08
+	Hs
		231491 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		KIF1B_HUMAN (22-927): 1.18e-124: 418: 16.49
+	Hs
		927565 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		KI13B_HUMAN (23-845): 2.95e-123: 414: 16.08
+	Hs
		231455 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		KIF1B_HUMAN (22-927): 1.18e-124: 418: 16.49
+	Hs
		855614 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		KIF11_HUMAN (10-711): 1.83e-114: 378: 19.63
+	Hs
		683642 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		KI20B_HUMAN (23-438): 3.71e-53: 204: 34.54
+	Dm
		54781 1433E_DROME (3-245): 4.63e-144: 405: 64.90		A1ZA18_DROME (215-463): 1.8e-32: 139: 38.74
+	Dm
		54779 1433Z_DROME (2-246): 4.79e-141: 396: 78.78		A1ZA18_DROME (215-463): 1.8e-32: 139: 38.74
+	Mm
		702835 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		KIF5A_MOUSE (18-147): 7.24e-19: 94.6: 32.33
+	Hs
		909493 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		KIF5A_HUMAN (18-147): 7.45e-19: 94.6: 32.33
+	Hs
		683303 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		KIF5A_HUMAN (18-147): 7.45e-19: 94.6: 32.33
+	Hs
		926981 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		KIF5A_HUMAN (18-147): 7.45e-19: 94.6: 32.33
+	Mm
		910349 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		KI21B_MOUSE (413-849): 6.3e-10: 65.7: 6.41
+	Hs
		253248 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		KI21B_HUMAN (413-849): 4.95e-10: 65.7: 6.64
+	Hs
		253246 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		KI21B_HUMAN (413-849): 4.95e-10: 65.7: 6.64