HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: AKTS1 (Q96B36)
Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate)
Gene: AKT1S1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.714

Property	Details
Experiments	33961781, 36931259, 24255178, 28514442, 18372248
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004860 - protein kinase inhibitor activity GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 246 Hs			1 256
+	Hs
		909890 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		AKTS1_HUMAN (1-256): 4.07e-135: 382: 100.00
+	Hs
		927386 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		AKTS1_HUMAN (1-256): 4.07e-135: 382: 100.00
+	Hs
		647174 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		AKTS1_HUMAN (1-256): 4.07e-135: 382: 100.00
+	Mm
		933141 1433T_MOUSE (3-244): 9.37e-127: 360: 81.82		AKTS1_MOUSE (1-256): 1.59e-121: 348: 92.61
+	Hs
		904962 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		AKTS1_HUMAN (1-256): 4.07e-135: 382: 100.00
+	Hs
		982365 1433F_HUMAN (4-244): 2.7e-107: 311: 75.51		AKTS1_HUMAN (1-256): 4.07e-135: 382: 100.00