HitPredict

Interactor 1: PTX3 (P26022)
Pentraxin-related protein PTX3 (Pentaxin-related protein PTX3) (Tumor necrosis factor alpha-induced protein 5) (TNF alpha-induced protein 5) (Tumor necrosis factor-inducible gene 14 protein) (TSG-14)
Gene: PTX3

Interactor 2: FGF22 (Q9HCT0)
Fibroblast growth factor 22 (FGF-22)
Gene: FGF22

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	25912421
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 381 Hs			1 170
+	Hs
		683756 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF20_HUMAN (12-169): 1.73e-71: 216: 43.13
+	Hs
		640747 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF7_HUMAN (25-170): 1.26e-68: 208: 45.58
+	Hs
		214097 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF16_HUMAN (29-169): 5.11e-68: 207: 44.06
+	Hs
		426940 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF1_HUMAN (37-170): 1.22e-56: 176: 37.04
+	Hs
		478451 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF2_HUMAN (3-167): 1.22e-54: 175: 30.12
+	Hs
		551530 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF5_HUMAN (41-167): 1.13e-50: 165: 38.35
+	Hs
		683718 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF8_HUMAN (39-168): 2.55e-43: 145: 24.81
+	Hs
		240136 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF17_HUMAN (39-168): 2.87e-42: 142: 29.32
+	Hs
		303362 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF18_HUMAN (39-167): 1.2e-42: 142: 25.76
+	Hs
		343716 NPTX1_HUMAN (70-377): 1.05e-99: 304: 25.32		FGF19_HUMAN (1-168): 8.02e-48: 156: 30.11