HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: CNTLN (Q9NXG0)
Centlein (Centrosomal protein)
Gene: CNTLN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019904 - protein domain specific binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1405
+	Hs
		910084 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		CNTLN_HUMAN (1-1397): 1.54e-82: 300: 100.00
+	Mm
		910250 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		GRDN_MOUSE (511-1377): 9.89e-30: 131: 15.58
+	Mm
		926795 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		GRDN_MOUSE (511-1377): 9.89e-30: 131: 15.58
+	Hs
		725130 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYH10_HUMAN (668-1405): 7.47e-26: 118: 9.04
+	Hs
		909975 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		CP250_HUMAN (8-837): 1.09e-25: 118: 9.28
+	Hs
		728460 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYH11_HUMAN (901-1405): 3.14e-25: 116: 10.69
+	Hs
		728466 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH11_HUMAN (901-1405): 3.14e-25: 116: 10.69
+	Mm
		926804 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MYH10_MOUSE (668-1404): 6.56e-25: 115: 9.83
+	Hs
		909625 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		GRDN_HUMAN (600-1400): 6.26e-22: 105: 14.01
+	Hs
		683394 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		GRDN_HUMAN (600-1400): 6.26e-22: 105: 14.01
+	Hs
		724761 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH9_HUMAN (911-1405): 8.25e-24: 111: 10.44
+	Mm
		926855 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MYH9_MOUSE (827-1403): 3.98e-22: 106: 10.24
+	Mm
		93548 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		DESP_MOUSE (66-833): 2.07e-20: 100: 12.60
+	Hs
		502907 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH3_HUMAN (876-1405): 2.25e-20: 100: 10.32
+	Zm
		5465 B6U284_MAIZE (3-243): 6.61e-144: 404: 63.27		A0A1D6DZK4_MAIZE (895-1403): 2.78e-17: 90.3: 10.29
+	Hs
		683277 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		CENPE_HUMAN (12-759): 1.08e-15: 85.3: 9.66
+	Mm
		926889 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		PLEC_MOUSE (543-1353): 4.02e-17: 90.3: 14.27
+	Hs
		522602 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH7_HUMAN (1060-1405): 1.14e-14: 81.8: 9.48
+	Hs
		551660 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DESP_HUMAN (317-1399): 1.07e-10: 69.1: 9.84
+	Hs
		927068 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PLEC_HUMAN (613-1298): 7.13e-09: 63: 13.48