HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: NDE1 (Q9NXR1)
Nuclear distribution protein nudE homolog 1 (NudE)
Gene: NDE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 335
+	Hs
		910085 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		NDE1_HUMAN (1-335): 2.68e-70: 224: 100.00
+	Mm
		910342 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		NDEL1_MOUSE (3-316): 7.82e-68: 217: 57.73
+	Hs
		927582 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		NDE1_HUMAN (1-335): 2.68e-70: 224: 100.00
+	Hs
		910002 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		NDEL1_HUMAN (3-316): 1.44e-65: 212: 56.78
+	Mm
		926882 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		NDEL1_MOUSE (3-316): 7.82e-68: 217: 57.73
+	Mm
		1321771 1433B_MOUSE (1-246): 5.56e-141: 396: 98.78		NDEL1_MOUSE (3-316): 7.82e-68: 217: 57.73
+	Hs
		728460 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYH11_HUMAN (9-205): 2.12e-42: 158: 19.80
+	Hs
		728466 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH11_HUMAN (9-205): 2.12e-42: 158: 19.80
+	Hs
		927644 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH13_HUMAN (3-243): 1.12e-35: 139: 12.03
+	Hs
		522602 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH7_HUMAN (3-226): 2.27e-35: 138: 12.95
+	Hs
		927643 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH2_HUMAN (3-226): 2.96e-35: 138: 14.29
+	Dm
		955038 1433E_DROME (3-245): 4.63e-144: 405: 64.90		NDE1_DROME (3-247): 5.27e-34: 128: 33.20
+	Hs
		502907 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH3_HUMAN (3-235): 1.67e-33: 133: 12.88
+	Hs
		724761 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH9_HUMAN (2-221): 3.6e-33: 131: 18.18
+	Hs
		725130 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYH10_HUMAN (2-205): 2.43e-27: 115: 20.10
+	Mm
		926855 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MYH9_MOUSE (9-212): 7.96e-29: 119: 18.14
+	Mm
		926804 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MYH10_MOUSE (2-205): 8.33e-27: 113: 19.61
+	Hs
		909658 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MRCKA_HUMAN (2-235): 6.8e-11: 65.7: 12.96
+	Hs
		683425 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		MRCKA_HUMAN (2-235): 6.8e-11: 65.7: 12.96
+	Hs
		927145 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MRCKA_HUMAN (2-235): 6.8e-11: 65.7: 12.96