HitPredict

Interactor 1: PTN3 (P26045)
Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1)
Gene: PTPN3

Interactor 2: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.748

Property	Details
Experiments	27880917, 27432908, 28330616, 28675297, 33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0017080 - sodium channel regulator activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 246
+	Hs
		683983 PTN3_HUMAN (1-913): 0: 865: 100.00		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		683982 PTN3_HUMAN (1-913): 0: 865: 100.00		1433G_HUMAN (1-246): 9.42e-138: 388: 86.99
+	Hs
		708841 PTN4_HUMAN (1-913): 0: 811: 50.11		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		708840 PTN4_HUMAN (1-913): 0: 811: 50.11		1433G_HUMAN (1-246): 9.42e-138: 388: 86.99
+	Hs
		708847 PTN4_HUMAN (1-913): 0: 811: 50.11		1433F_HUMAN (1-246): 6.11e-136: 383: 100.00
+	Hs
		683984 PTN3_HUMAN (1-913): 0: 865: 100.00		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		683969 PTN3_HUMAN (1-913): 0: 865: 100.00		1433B_HUMAN (3-245): 2.72e-107: 311: 75.51
+	Hs
		683965 PTN3_HUMAN (1-913): 0: 865: 100.00		1433T_HUMAN (3-245): 7.22e-106: 307: 71.43
+	Hs
		683970 PTN3_HUMAN (1-913): 0: 865: 100.00		1433S_HUMAN (3-245): 2.77e-96: 283: 64.20
+	Hs
		708844 PTN4_HUMAN (1-913): 0: 811: 50.11		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		708832 PTN4_HUMAN (1-913): 0: 811: 50.11		1433B_HUMAN (3-245): 2.72e-107: 311: 75.51
+	Hs
		690756 PTN4_HUMAN (1-913): 0: 811: 50.11		1433T_HUMAN (3-245): 7.22e-106: 307: 71.43
+	Hs
		971997 E41L1_HUMAN (8-666): 1.06e-128: 410: 23.09		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		966871 E41L1_HUMAN (8-666): 1.06e-128: 410: 23.09		1433G_HUMAN (1-246): 9.42e-138: 388: 86.99
+	Hs
		1049782 E41L1_HUMAN (8-666): 1.06e-128: 410: 23.09		1433F_HUMAN (1-246): 6.11e-136: 383: 100.00
+	Hs
		990729 E41L1_HUMAN (8-666): 1.06e-128: 410: 23.09		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		730240 E41L1_HUMAN (8-666): 1.06e-128: 410: 23.09		1433B_HUMAN (3-245): 2.72e-107: 311: 75.51
+	Hs
		730267 E41L5_HUMAN (10-660): 5.72e-129: 407: 22.00		1433B_HUMAN (3-245): 2.72e-107: 311: 75.51
+	Hs
		691429 E41L1_HUMAN (8-666): 1.06e-128: 410: 23.09		1433T_HUMAN (3-245): 7.22e-106: 307: 71.43
+	Hs
		691456 E41L5_HUMAN (10-660): 5.72e-129: 407: 22.00		1433T_HUMAN (3-245): 7.22e-106: 307: 71.43