HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: ARHG5 (Q12774)
Rho guanine nucleotide exchange factor 5 (Ephexin-3) (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (Transforming immortalized mammary oncogene) (p60 TIM)
Gene: ARHGEF5

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	15778465, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1597
+	Hs
		909489 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ARHG5_HUMAN (1-1597): 7.13e-161: 532: 100.00
+	Hs
		926975 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ARHG5_HUMAN (1-1597): 7.13e-161: 532: 100.00
+	Hs
		646839 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		ARHG5_HUMAN (1-1597): 7.13e-161: 532: 100.00
+	Hs
		684271 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SPT13_HUMAN (903-1510): 2.45e-96: 327: 11.93
+	Hs
		684104 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ARHGG_HUMAN (895-1589): 9.42e-89: 307: 25.63
+	Hs
		909921 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SPT13_HUMAN (903-1510): 2.45e-96: 327: 11.93
+	Hs
		909781 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ARHGJ_HUMAN (802-1595): 3.23e-94: 326: 36.36
+	Hs
		910068 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ARHG4_HUMAN (884-1536): 3.94e-90: 311: 13.16
+	Hs
		909662 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ARHGG_HUMAN (895-1589): 9.42e-89: 307: 25.63
+	Hs
		927416 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		SPT13_HUMAN (903-1510): 2.45e-96: 327: 11.93
+	Hs
		927568 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ARHG4_HUMAN (884-1536): 3.94e-90: 311: 13.16
+	Mm
		926773 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		RGRF2_MOUSE (1009-1572): 7.06e-85: 306: 13.61
+	Hs
		927148 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ARHGG_HUMAN (895-1589): 9.42e-89: 307: 25.63
+	Hs
		927539 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ECT2_HUMAN (1113-1497): 1.4e-83: 297: 22.14
+	Hs
		647196 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		SPT13_HUMAN (903-1510): 2.45e-96: 327: 11.93
+	Hs
		684147 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		FGD6_HUMAN (1033-1545): 3.44e-49: 194: 15.16
+	Hs
		646986 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		ARHGG_HUMAN (895-1589): 9.42e-89: 307: 25.63
+	Hs
		909717 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		FGD6_HUMAN (1033-1545): 3.44e-49: 194: 15.16
+	Hs
		927201 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		FGD6_HUMAN (1033-1545): 3.44e-49: 194: 15.16
+	Hs
		647028 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		FGD6_HUMAN (1033-1545): 3.44e-49: 194: 15.16