HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: GAB1 (Q13480)
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
Gene: GAB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 694
+	Hs
		909527 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Hs
		684404 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		GAB2_HUMAN (3-691): 2.24e-153: 461: 39.01
+	Hs
		910172 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		GAB2_HUMAN (3-691): 2.24e-153: 461: 39.01
+	Mm
		910246 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		Q3ZB59_MOUSE (3-691): 1.2e-140: 428: 38.33
+	Hs
		684083 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		DOC11_HUMAN (3-563): 1.15e-114: 381: 13.19
+	Mm
		926898 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		GAB2_MOUSE (3-691): 8.7e-141: 429: 38.33
+	Mm
		926790 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		Q3ZB59_MOUSE (3-691): 1.2e-140: 428: 38.33
+	Hs
		909993 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DOCK9_HUMAN (3-556): 1.29e-117: 390: 14.81
+	Hs
		909638 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DOC11_HUMAN (3-563): 1.15e-114: 381: 13.19
+	Hs
		63199 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		A6NIW2_HUMAN (3-563): 1.15e-114: 381: 13.19
+	Hs
		684119 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PKHA7_HUMAN (5-485): 5.86e-74: 260: 12.07
+	Hs
		684333 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PKHA5_HUMAN (5-476): 6.15e-67: 240: 13.00
+	Hs
		909680 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PKHA7_HUMAN (5-485): 5.86e-74: 260: 12.07
+	Hs
		910040 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PKHA5_HUMAN (5-476): 6.15e-67: 240: 13.00
+	Mm
		926832 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		CNKR2_MOUSE (7-393): 1.86e-56: 210: 16.38
+	Hs
		684334 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PKHA1_HUMAN (6-156): 1.25e-32: 132: 25.49
+	Hs
		910041 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PKHA2_HUMAN (2-210): 3.77e-36: 143: 19.28
+	Hs
		910043 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PKHA1_HUMAN (6-156): 1.25e-32: 132: 25.49
+	Hs
		297821 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		K0754_HUMAN (339-656): 1.08e-09: 64.4: 11.22
+	Hs
		297824 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		K0754_HUMAN (339-656): 1.08e-09: 64.4: 11.22