HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: RGPA1 (Q6GYQ0)
Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240)
Gene: RALGAPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 2036
+	Hs
		909678 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		196406 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SI1L1_HUMAN (1683-2015): 2.28e-106: 380: 19.22
+	Hs
		684372 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SI1L2_HUMAN (1694-2016): 4.06e-106: 379: 18.88
+	Hs
		230209 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SI1L3_HUMAN (1691-2016): 1.32e-100: 362: 18.83
+	Hs
		909669 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RPGP2_HUMAN (1630-2013): 1.11e-114: 384: 19.90
+	Hs
		196427 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SI1L1_HUMAN (1683-2015): 2.28e-106: 380: 19.22
+	Hs
		683908 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		TSC2_HUMAN (1727-2033): 1.18e-96: 349: 23.90
+	Hs
		910116 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SI1L2_HUMAN (1694-2016): 4.06e-106: 379: 18.88
+	Hs
		909769 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		230231 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SI1L3_HUMAN (1691-2016): 1.32e-100: 362: 18.83
+	Hs
		196429 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		SI1L1_HUMAN (1683-2015): 2.28e-106: 380: 19.22
+	Hs
		683896 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		RPGP1_HUMAN (1627-2013): 3.28e-93: 319: 18.30
+	Hs
		835035 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		TSC2_HUMAN (1727-2033): 1.18e-96: 349: 23.90
+	Hs
		230235 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		SI1L3_HUMAN (1691-2016): 1.32e-100: 362: 18.83
+	Hs
		835039 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		TSC2_HUMAN (1727-2033): 1.18e-96: 349: 23.90
+	Hs
		812874 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RPGP1_HUMAN (1627-2013): 3.28e-93: 319: 18.30
+	Hs
		812876 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RPGP1_HUMAN (1627-2013): 3.28e-93: 319: 18.30
+	Dm
		114606 1433E_DROME (2-247): 2.8e-144: 405: 58.07		M9PD17_DROME (1750-2010): 4.88e-74: 277: 25.18
+	Dm
		955043 1433E_DROME (2-247): 2.8e-144: 405: 58.07		Q9VW83_DROME (1750-2010): 5.15e-74: 277: 25.18
+	Mm
		926787 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		Q3TQ10_MOUSE (1840-2034): 1.27e-76: 256: 22.17