HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: LNX2 (Q8N448)
Ligand of Numb protein X 2 (Numb-binding protein 2) (PDZ domain-containing RING finger protein 1)
Gene: LNX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.50	0.512

Property	Details
Experiments	27107012
Identification Methods	two hybrid, barcode fusion genetics two hybrid, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 690
+	Mm
		926859 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		LNX2_MOUSE (1-690): 1.46e-138: 424: 89.73
+	Hs
		927328 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		LNX1_HUMAN (12-690): 1.54e-118: 373: 45.07
+	Mm
		250606 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		LNX1_MOUSE (16-690): 3.38e-117: 369: 44.90
+	Mm
		910260 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		DLG4_MOUSE (412-690): 3.63e-33: 138: 20.07
+	Hs
		684003 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PTN13_HUMAN (71-499): 1.04e-21: 103: 12.73
+	Mm
		926805 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		DLG4_MOUSE (412-690): 3.63e-33: 138: 20.07
+	Hs
		684228 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PARD3_HUMAN (473-672): 1.31e-14: 80.1: 29.13
+	Hs
		909498 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PTN13_HUMAN (71-499): 1.04e-21: 103: 12.73
+	Mm
		250875 1433S_MOUSE (1-248): 4.84e-154: 429: 97.58		PARD3_MOUSE (473-672): 1.48e-15: 83.2: 29.13
+	Hs
		684030 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SCRIB_HUMAN (215-592): 4.05e-12: 72: 11.68
+	Hs
		684280 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MAGI1_HUMAN (558-670): 1.23e-10: 67.1: 25.83
+	Hs
		684229 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PAR3L_HUMAN (339-544): 2.67e-10: 65.9: 27.23
+	Hs
		909852 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PARD3_HUMAN (473-672): 1.31e-14: 80.1: 29.13
+	Dm
		677686 1433E_DROME (2-247): 2.8e-144: 405: 58.07		DLG1_DROME (543-688): 4.16e-16: 84.5: 31.08
+	Hs
		926984 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		PTN13_HUMAN (71-499): 1.04e-21: 103: 12.73
+	Hs
		909853 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PAR3L_HUMAN (339-544): 2.67e-10: 65.9: 27.23
+	Hs
		927337 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		PARD3_HUMAN (473-672): 1.31e-14: 80.1: 29.13
+	Hs
		927034 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		SCRIB_HUMAN (215-592): 4.05e-12: 72: 11.68
+	Hs
		927338 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		PAR3L_HUMAN (339-544): 2.67e-10: 65.9: 27.23
+	Hs
		646848 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		PTN13_HUMAN (71-499): 1.04e-21: 103: 12.73