HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: KKCC1 (Q8N5S9)
Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)
Gene: CAMKK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 505
+	Hs
		909813 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		KKCC1_HUMAN (1-505): 2.94e-159: 463: 100.00
+	Rn
		910354 1433E_RAT (2-246): 4.41e-146: 410: 60.41		KKCC1_RAT (1-505): 3.01e-153: 448: 93.66
+	Hs
		684282 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		KKCC2_HUMAN (31-504): 7.59e-134: 401: 59.49
+	Hs
		681682 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		AKT1_HUMAN (60-474): 9.07e-130: 387: 21.33
+	At
		1280891 14337_ARATH (2-247): 4.35e-147: 413: 58.07		CIPKC_ARATH (103-501): 1.35e-132: 395: 23.47
+	At
		788672 14333_ARATH (3-247): 2.63e-144: 405: 58.30		CIPKC_ARATH (103-501): 1.35e-132: 395: 23.47
+	Dm
		90534 1433E_DROME (2-247): 2.8e-144: 405: 58.07		E1JGN0_DROME (20-415): 1.71e-125: 395: 28.29
+	At
		965360 14332_ARATH (3-248): 2.23e-144: 405: 58.47		CIPKC_ARATH (103-501): 1.35e-132: 395: 23.47
+	Hs
		681770 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		AKT1_HUMAN (60-474): 9.07e-130: 387: 21.33
+	Hs
		647107 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		KKCC1_HUMAN (1-505): 2.94e-159: 463: 100.00
+	Hs
		681776 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		AKT1_HUMAN (60-474): 9.07e-130: 387: 21.33
+	Hs
		683541 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		KKCC1_HUMAN (1-505): 2.94e-159: 463: 100.00
+	Hs
		904856 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		KKCC1_HUMAN (1-505): 2.94e-159: 463: 100.00
+	Hs
		982274 1433F_HUMAN (2-242): 2.78e-96: 283: 64.20		KKCC1_HUMAN (1-505): 2.94e-159: 463: 100.00
+	Rn
		716562 1433B_RAT (1-239): 5.05e-100: 293: 69.04		KKCC1_RAT (1-505): 3.01e-153: 448: 93.66
+	Rn
		905365 1433G_RAT (1-242): 1.86e-98: 289: 65.16		KKCC1_RAT (1-505): 3.01e-153: 448: 93.66
+	Rn
		935723 1433F_RAT (2-242): 1.72e-96: 284: 64.20		KKCC1_RAT (1-505): 3.01e-153: 448: 93.66
+	Hs
		681766 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		AKT1_HUMAN (60-474): 9.07e-130: 387: 21.33
+	Sp
		788705 RAD24_SCHPO (2-248): 5.1e-136: 385: 54.66		SSP1_SCHPO (125-441): 6.2e-65: 223: 41.09
+	Zm
		31741 A0A1D6KKP0_MAIZE (1-247): 6.14e-142: 399: 57.83		B4FIX4_MAIZE (125-439): 2.04e-54: 190: 38.41