HitPredict

Interactor 1: RUXGL (A8MWD9)
Putative small nuclear ribonucleoprotein G-like protein 15
Gene: SNRPGP15

Interactor 2: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	GTP_EFTU~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 76 Hs			1 972
+	Hs
		912044 RUXG_HUMAN (1-76): 5.34e-30: 102: 94.74		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		1064819 LSM7_HUMAN (3-76): 1.31e-24: 89.8: 31.71		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		927954 RSMN_HUMAN (1-70): 9.31e-23: 88.6: 21.25		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		911839 RUXF_HUMAN (5-73): 9.05e-24: 87.1: 26.09		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		538964 RSMB_HUMAN (1-70): 5.01e-22: 86.7: 21.25		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		321402 LSM8_HUMAN (8-75): 2.53e-19: 76: 23.61		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		167690 LSM1_HUMAN (5-74): 1.01e-17: 72.9: 30.14		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Sp
		252592 RUXG_SCHPO (1-76): 6.57e-25: 89.4: 47.37		SN114_SCHPO (1-970): 0: 928: 54.22
+	Sp
		223537 RUXF_SCHPO (1-72): 1.39e-23: 86.3: 24.00		SN114_SCHPO (1-970): 0: 928: 54.22
+	Sc
		731738 LSM1_YEAST (3-74): 3.52e-22: 85.6: 27.27		SN114_YEAST (3-967): 0: 692: 32.82
+	Sc
		731731 RUXG_YEAST (7-76): 5.33e-22: 82.3: 50.69		SN114_YEAST (3-967): 0: 692: 32.82
+	Sc
		731752 RUXF_YEAST (5-73): 2.81e-21: 80.6: 24.29		SN114_YEAST (3-967): 0: 692: 32.82
+	Sc
		731750 LSM7_YEAST (3-75): 1.4e-18: 74.8: 30.95		SN114_YEAST (3-967): 0: 692: 32.82
+	Sc
		731753 LSM3_YEAST (4-72): 4.33e-10: 52.6: 28.57		SN114_YEAST (3-967): 0: 692: 32.82
+	Zm
		5855 B4FMM6_MAIZE (1-76): 1.53e-23: 86.3: 55.84		A0A1D6E4M0_MAIZE (120-924): 0: 579: 20.35
+	Sc
		810526 LSM1_YEAST (3-74): 3.52e-22: 85.6: 27.27		RIA1_YEAST (111-485): 9.79e-110: 367: 26.97