HitPredict

Interactor 1: HOME3 (Q9NSC5)
Homer protein homolog 3 (Homer-3)
Gene: HOMER3

Interactor 2: ABI3 (Q9P2A4)
ABI gene family member 3 (New molecule including SH3) (Nesh)
Gene: ABI3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.671

Property	Details
Experiments	32296183, 19060904, unassigned1304
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0014069 - postsynaptic density
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 361 Hs			1 366
+	Hs
		1345493 HOME2_HUMAN (4-357): 6.53e-96: 291: 45.35		ABI3_HUMAN (1-366): 1.12e-87: 270: 100.00
+	Hs
		1205736 HOME1_HUMAN (4-360): 1.39e-87: 269: 50.42		ABI3_HUMAN (1-366): 1.12e-87: 270: 100.00
+	Hs
		282372 HOME3_HUMAN (1-361): 2.61e-97: 294: 100.00		NEBL_HUMAN (13-363): 2.92e-35: 139: 14.13
+	Hs
		1237895 ENAH_HUMAN (4-156): 1.76e-39: 149: 27.39		ABI3_HUMAN (1-366): 1.12e-87: 270: 100.00
+	Hs
		840593 VASP_HUMAN (4-170): 7.18e-35: 133: 23.12		ABI3_HUMAN (1-366): 1.12e-87: 270: 100.00
+	Hs
		1345510 HOME3_HUMAN (1-361): 2.61e-97: 294: 100.00		ABI2_HUMAN (109-363): 4.36e-25: 108: 23.18
+	Hs
		1224647 HOME3_HUMAN (1-361): 2.61e-97: 294: 100.00		ABI1_HUMAN (124-363): 7.31e-21: 95.5: 24.49
+	Hs
		1205704 HOME1_HUMAN (4-360): 1.39e-87: 269: 50.42		ABI1_HUMAN (124-363): 7.31e-21: 95.5: 24.49
+	Hs
		1349279 EP15R_HUMAN (78-354): 2.27e-57: 201: 14.74		ITSN2_HUMAN (306-365): 5.38e-13: 72.7: 37.50
+	Hs
		924919 EP15R_HUMAN (78-354): 2.27e-57: 201: 14.74		GRB2_HUMAN (312-363): 4.03e-14: 72.7: 28.30
+	Hs
		61738 EP15R_HUMAN (78-354): 2.27e-57: 201: 14.74		A6H8W8_HUMAN (306-365): 7.08e-13: 72.3: 37.50
+	Hs
		282318 VASP_HUMAN (4-170): 7.18e-35: 133: 23.12		NEBL_HUMAN (13-363): 2.92e-35: 139: 14.13
+	Hs
		1078923 EP15R_HUMAN (78-354): 2.27e-57: 201: 14.74		ITSN1_HUMAN (205-363): 8.02e-10: 62.8: 15.85
+	Mm
		1141846 EP15R_MOUSE (78-353): 1.02e-52: 189: 14.44		ITSN1_MOUSE (294-363): 7.17e-13: 72.1: 35.14
+	Hs
		1237890 ENAH_HUMAN (4-156): 1.76e-39: 149: 27.39		ABI2_HUMAN (109-363): 4.36e-25: 108: 23.18
+	Hs
		1224613 ENAH_HUMAN (4-156): 1.76e-39: 149: 27.39		ABI1_HUMAN (124-363): 7.31e-21: 95.5: 24.49
+	Hs
		840586 VASP_HUMAN (4-170): 7.18e-35: 133: 23.12		ABI2_HUMAN (109-363): 4.36e-25: 108: 23.18
+	Dm
		1250361 ENA_DROME (2-163): 7.97e-35: 137: 18.82		Q9Y0S9_DROME (260-364): 1.16e-20: 94.7: 38.32
+	Hs
		840522 VASP_HUMAN (4-170): 7.18e-35: 133: 23.12		ABI1_HUMAN (124-363): 7.31e-21: 95.5: 24.49
+	Hs
		840452 VASP_HUMAN (4-170): 7.18e-35: 133: 23.12		GRB2_HUMAN (312-363): 4.03e-14: 72.7: 28.30