HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: TSSK2 (Q96PF2)
Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) (EC 2.7.11.1) (DiGeorge syndrome protein G) (DGS-G) (Serine/threonine-protein kinase 22B)
Gene: TSSK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 358
+	Hs
		684303 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		TSSK1_HUMAN (1-336): 8.66e-147: 420: 67.61
+	Hs
		909980 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		TSSK1_HUMAN (1-336): 8.66e-147: 420: 67.61
+	At
		1280891 14337_ARATH (2-247): 4.35e-147: 413: 58.07		CIPKC_ARATH (2-333): 3.57e-135: 395: 31.05
+	Hs
		683925 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SIK1_HUMAN (7-283): 1.97e-119: 364: 40.50
+	Hs
		909927 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		TSSK2_HUMAN (1-358): 2.62e-135: 391: 100.00
+	At
		965291 14332_ARATH (3-248): 2.23e-144: 405: 58.47		CDPK1_ARATH (4-355): 2.54e-131: 390: 24.38
+	Hs
		883214 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SIK1_HUMAN (7-283): 1.97e-119: 364: 40.50
+	Hs
		684316 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SIK2_HUMAN (12-272): 8.36e-52: 186: 39.85
+	Hs
		684412 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SIK3_HUMAN (12-273): 3.37e-51: 185: 37.88
+	Hs
		647836 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MARK3_HUMAN (18-272): 2.86e-51: 183: 39.92
+	Hs
		684157 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MARK2_HUMAN (18-272): 5.69e-51: 183: 38.52
+	Hs
		910013 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SIK2_HUMAN (12-272): 8.36e-52: 186: 39.85
+	Hs
		910187 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SIK3_HUMAN (12-273): 3.37e-51: 185: 37.88
+	Hs
		909916 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MARK4_HUMAN (18-272): 1.8e-51: 184: 39.15
+	Mm
		910231 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		MARK3_MOUSE (18-272): 2.05e-51: 184: 40.39
+	Mm
		910308 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		MARK4_MOUSE (18-272): 2.03e-51: 184: 39.15
+	Hs
		647862 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MARK3_HUMAN (18-272): 2.86e-51: 183: 39.92
+	Hs
		909730 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MARK2_HUMAN (18-272): 5.69e-51: 183: 38.52
+	Xl
		223344 O57468_XENLA (2-246): 5.73e-145: 407: 60.00		Q804T2_XENLA (18-272): 6.32e-52: 185: 40.39
+	Xl
		223345 O57468_XENLA (2-246): 5.73e-145: 407: 60.00		Q8QGV3_XENLA (18-272): 4.75e-51: 183: 38.91