HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: PP12C (Q9BZL4)
Protein phosphatase 1 regulatory subunit 12C (Protein phosphatase 1 myosin-binding subunit of 85 kDa) (Protein phosphatase 1 myosin-binding subunit p85)
Gene: PPP1R12C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 782
+	Hs
		927494 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		PP12C_HUMAN (1-782): 1.36e-154: 471: 100.00
+	Hs
		684336 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		TANC2_HUMAN (4-720): 4.19e-69: 250: 16.47
+	Hs
		60315 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		POTEF_HUMAN (2-655): 2.1e-72: 258: 14.76
+	Hs
		910048 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		TANC2_HUMAN (4-720): 4.19e-69: 250: 16.47
+	Hs
		60317 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		POTEF_HUMAN (2-655): 2.1e-72: 258: 14.76
+	Hs
		927552 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		TANC2_HUMAN (4-720): 4.19e-69: 250: 16.47
+	Hs
		60298 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		POTEF_HUMAN (2-655): 2.1e-72: 258: 14.76
+	Mm
		56841 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		TANC2_MOUSE (84-371): 2.22e-38: 156: 18.85
+	Hs
		161313 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MYPT1_HUMAN (542-782): 1.47e-22: 105: 33.61
+	Mm
		56842 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		TANC2_MOUSE (84-371): 2.22e-38: 156: 18.85
+	Hs
		257573 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ANR17_HUMAN (157-476): 3.34e-19: 95.6: 10.64
+	Hs
		909455 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ANK2_HUMAN (192-510): 1.07e-25: 116: 13.86
+	Mm
		57343 1433S_MOUSE (1-248): 4.84e-154: 429: 97.58		A2AM57_MOUSE (180-380): 2.48e-17: 89: 13.93
+	Hs
		161349 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MYPT1_HUMAN (542-782): 1.47e-22: 105: 33.61
+	Hs
		257595 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ANR17_HUMAN (157-476): 3.34e-19: 95.6: 10.64
+	Hs
		926936 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ANK2_HUMAN (192-510): 1.07e-25: 116: 13.86
+	Hs
		161353 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MYPT1_HUMAN (542-782): 1.47e-22: 105: 33.61
+	Hs
		257597 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ANR17_HUMAN (157-476): 3.34e-19: 95.6: 10.64
+	Hs
		909789 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ANKH1_HUMAN (3-122): 8.29e-10: 64.7: 16.67
+	Mm
		57379 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		A2AM57_MOUSE (180-380): 2.48e-17: 89: 13.93