HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 956
+	Hs
		910060 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		927563 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		647304 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		683740 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		905148 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		982530 1433F_HUMAN (2-242): 2.78e-96: 283: 64.20		CYLD_HUMAN (1-956): 0: 1872: 100.00